Results 51 to 60 of about 681,909 (305)

Modern prospects of laboratory diagnosis of acute respiratory diseases and influenza

open access: yesAktualʹnaâ Infektologiâ, 2020
The article presents an analysis of the available sources of scientific literature on modern aspects of laboratory diagnosis of acute respiratory diseases and influenza.
I.A. Anastasii, V.M. Isaiev
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Acute Exacerbations of Respiratory Diseases [PDF]

open access: yesCritical Care, 2012
Steven Sahn: Acute Exacerbations of Respiratory Diseases.
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Epidemiological and morbidity pattern of respiratory diseases in children admitted in the paediatric ward of a tertiary hospital in Southern Nigeria

open access: yesIbom Medical Journal, 2020
Context: Respiratory tract diseases contribute a majority of paediatric admissions and are a major cause of death in children less than five years. Objective: To assess the epidemiological and morbidity patterns of respiratory disease in children ...
Oloyede IP, Ekrikpo UE
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

New therapeutic opportunities of phytopreparations in the treatment of acute respiratory infections in children

open access: yesZdorovʹe Rebenka, 2019
We consider it is reasonable to use symptomatic therapy in all cases of uncomplicated acute respiratory viral infections, which are self-eliminating diseases.
E.A. Agafonova   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The incidence of non-tumour diseases of the respiratory organs of offspring of the first generation of residents of radiation-contaminated territories of Ukraine under the age of 18 years

open access: yesJournal of Education, Health and Sport, 2019
There was conducted an epidemiological study of the morbidity of non-tumour diseases of the respiratory organs of the first-generation offspring born by residents of radioactively contaminated territories, until they reached 18 years.
Zh. Yaroshenko
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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