Results 161 to 170 of about 233,117 (249)

The utility of C‐reactive protein in neonatal early‐onset sepsis screening: A territory‐wide cohort analysis

open access: yesPediatric Investigation, EarlyView.
C‐reactive protein (CRP) is not recommended for early‐onset sepsis (EOS) screening in term neonates. CRP results can support EOS risk assessment in preterm neonates, but should be interpreted appropriately with other clinical parameters. A CRP level of >12.0 mg/L may suggest the need for lumbar puncture during sepsis evaluation.
Xuelian Wang   +4 more
wiley   +1 more source

Challenges and Opportunities in State‐of‐the‐Art Proteomics Analysis for Biomarker Development From Plasma Extracellular Vesicles

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound particles secreted by cells, playing crucial roles in intercellular communication. The composition of EVs can undergo changes in response to stress and disease conditions, making them excellent biomarker candidates.
Panshak P. Dakup   +11 more
wiley   +1 more source

Olfactomedin-4 elevation in pediatric acute respiratory distress syndrome. [PDF]

open access: yesAm J Physiol Lung Cell Mol Physiol
O'Sullivan R   +5 more
europepmc   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said   +10 more
wiley   +1 more source

A Novel Method Using Dual‐Energy Computed Tomography for Detecting Amiodarone‐Induced Lung Injury: A Cohort Pilot Study

open access: yesRespirology, EarlyView.
There is no gold standard for detecting amiodarone‐induced‐lung injury (AILD). Dual‐Energy‐Computed‐Tomography (DECT) depicts iodine deposition in lungs abnormalities and the liver. We found a substantial correlation between the DECT assessment of AILD and comprehensive clinical evaluation of AILD. DECT can assist in the diagnosis of AILD.
Naama R. Bogot   +8 more
wiley   +1 more source

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