Results 21 to 30 of about 548,774 (332)

Biomarker-Based Classification of Patients With Acute Respiratory Failure Into Inflammatory Subphenotypes: A Single-Center Exploratory Study

Critical Care Explorations, 2021
OBJECTIVES:. Hyper- and hypoinflammatory subphenotypes discovered in patients with acute respiratory distress syndrome predict clinical outcomes and therapeutic responses. These subphenotypes may be important in broader critically ill patient populations
Callie M. Drohan, MD, S. Mehdi Nouraie, MD, PhD, William Bain, MD, Faraaz A. Shah, MD, MPH, John Evankovich, MD, Yingze Zhang, PhD, Alison Morris, MD, MS, Bryan J. McVerry, MD, Georgios D. Kitsios, MD, PhD   +8 more
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Use of Machine Learning to Screen for Acute Respiratory Distress Syndrome Using Raw Ventilator Waveform Data

Critical Care Explorations, 2021
Objectives:. To develop and characterize a machine learning algorithm to discriminate acute respiratory distress syndrome from other causes of respiratory failure using only ventilator waveform data. Design:.
Gregory B. Rehm, MS, Irene Cortés-Puch, MD, Brooks T. Kuhn, MD, MAS, Jimmy Nguyen, RRT, Sarina A. Fazio, PhD, RN, Michael A. Johnson, MD, PhD, Nicholas R. Anderson, PhD, Chen-Nee Chuah, PhD, Jason Y. Adams, MD, MS   +8 more
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Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome

Blood, 2020
COVID-19 affects millions of patients worldwide, with clinical presentation ranging from isolated thrombosis to acute respiratory distress syndrome (ARDS) requiring ventilator support.
E. Middleton, Xue-Yan He, F. Denorme, Robert A. Campbell, David Ng, S. Salvatore, Maria Mostyka, Amelia Baxter-Stoltzfus, A. Borczuk, M. Loda, M. Cody, B. Manne, Irina Portier, Estelle M. Harris, Aaron C Petrey, E. Beswick, Aleah F. Caulin, A. Iovino, Lisa M. Abegglen, A. Weyrich, M. Rondina, M. Egeblad, J. Schiffman, C. C. Yost   +23 more
semanticscholar   +1 more source

An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline

American Journal of Respiratory and Critical Care Medicine, 2023
Background This document updates previously published Clinical Practice Guidelines for the management of patients with acute respiratory distress syndrome (ARDS), incorporating new evidence addressing the use of corticosteroids, venovenous extracorporeal
N. Qadir, S. Sahetya, L. Munshi, Charlotte Summers, D. Abrams, J. Beitler, G. Bellani, Roy G. Brower, L. Burry, Jen-Ting Chen, C. Hodgson, Catherine L. Hough, F. Lamontagne, A. Law, L. Papazian, Tái Pham, Eileen Rubin, M. Siuba, I. Telias, S. Patolia, Dipayan Chaudhuri, Allan J. Walkey, B. Rochwerg, E. Fan   +23 more
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COVID-19 Does Not Lead to a “Typical” Acute Respiratory Distress Syndrome

American Journal of Respiratory and Critical Care Medicine, 2020
ventilation strategy was applied to the first four patients to increase pulmonary efficiency to eliminate CO2, and this was used in the next four patients. Gas exchange consists of oxygenation and ventilation.
L. Gattinoni, S. Coppola, M. Cressoni, M. Busana, D. Chiumello   +4 more
semanticscholar   +1 more source

Adherence to Lung Protective Ventilation in Patients With Coronavirus Disease 2019

Critical Care Explorations, 2021
OBJECTIVES:. Prior studies have demonstrated suboptimal adherence to lung protective ventilation among patients with acute respiratory distress syndrome. A common barrier to providing this evidence-based practice is diagnostic uncertainty.
Elizabeth Levy, MD, Stefania Scott, MS, Teresa Tran, MPH, Wei Wang, PhD, Mark E. Mikkelsen, MD, MSCE, Barry D. Fuchs, MD, Meeta Prasad Kerlin, MD, MSCE   +6 more
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A case report of severe hypothermia complicated by acute respiratory distress syndrome

Respiratory Medicine Case Reports, 2019
Acute respiratory distress syndrome has not been a described complication of hypothermia. Causes of hypothermia are commonly associated with alcohol abuse and infection, both of which could lead to acute respiratory distress syndrome.
C. Vahdatpour, A. Sussman, T. Mahr
doaj   +1 more source

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

Science immunology, 2020
Peptide pool stimulation enables longitudinal analysis of SARS-CoV-2-specific CD4+ and CD8+ T cells in ICU-admitted COVID-19 patients. SARS-CoV-2 has been identified as the causative agent of a global outbreak of respiratory tract disease (COVID-19).
D. Weiskopf, K. Schmitz, M. Raadsen, A. Grifoni, Nisreen M. A. Okba, H. Endeman, J. P. van den Akker, R. Molenkamp, M. Koopmans, E. V. van Gorp, B. Haagmans, R. D. de Swart, A. Sette, R. D. de Vries   +13 more
semanticscholar   +1 more source

Plasma Metabolites in Early Sepsis Identify Distinct Clusters Defined by Plasma Lipids

Critical Care Explorations, 2021
OBJECTIVES:. Unbiased global metabolomic profiling has not been used to identify distinct subclasses in patients with early sepsis and sepsis-associated acute respiratory distress syndrome.
Angela J. Rogers, MD, MPH, Aleksandra Leligdowicz, MD, PhD, Kévin Contrepois, PhD, Alejandra Jauregui, BSc, Kathryn Vessel, BSc, Thomas J. Deiss, BSc, Annika Belzer, BSc, Tom Liu, MD, Matthew Lippi, MD, MPH, Serena Ke, BSc, Erin Ross, BSc, Hanjing Zhou, MSc, Carolyn Hendrickson, MD, MAS, Antonio Gomez, MD, Pratik Sinha, MD, PhD, Kirsten N. Kangelaris, MD, Kathleen D. Liu, MD, PhD, Carolyn S. Calfee, MD, MAS, Michael A. Matthay, MD   +18 more
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Guideline-based management of acute respiratory failure and acute respiratory distress syndrome

Journal of Intensive Care, 2023
Acute respiratory failure (ARF) is defined by acute and progressive hypoxemia caused by various cardiorespiratory or systemic diseases in previously healthy patients.
S. Fujishima
semanticscholar   +1 more source