Results 41 to 50 of about 233,117 (249)

Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2‐Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction

Advanced Science, EarlyView.
SCAP/ARDS patients show reduced unsaturated fatty acids (UFAs) but higher PARK7 and lactate in plasma. PARK7 correlates positively with lactate and negatively with UFAs. Pulmonary endothelial cell multi‐omics show FADS1/2 downregulation and impaired PUFA metabolism. Lactate boosts PARK7 via H3K14 lactylation, and PARK7 then restores FADS1/2.
Jian Xu, Yuhan Wang, Weiqi Mao, Tianchang Wei, Yufan Li, Juan Song, Cuiping Zhang, Xiaoyan Chen, Cuicui Chen, Qingyuan Xu, Xu Wu, Yuanlin Song   +11 more
wiley   +1 more source

Successful application of airway pressure release ventilation in a child with severe acute respiratory distress syndrome induced by trauma: a case report

BMC Pulmonary Medicine
Background Trauma has been identified as one of the risk factors for acute respiratory distress syndrome. Respiratory support can be further complicated by comorbidities of trauma such as primary or secondary lung injury.
Jing Su, Xin Tie, Yao Chen, Tongjuan Zou, Wanhong Yin   +4 more
doaj   +1 more source

High frequency ventilation in acute respiratory distress syndrome: a case report [PDF]

Einstein (São Paulo), 2005
Acute Respiratory Distress Syndrome is a common entity thataffects patients with serious conditions and has a high mortalityrate. It was published ten years ago that pulmonary protectiveventilation, with low tidal volumes and high respiratory frequencies,
Carolina Friedrich Amoretti, Nelson Hamerschlak, Lucília Santana Faria, Luciana Branco Haddad, Eduardo Juan Troster   +4 more
doaj  

Eosinophilic infiltrate in a patient with severe Legionella pneumonia as a levofloxacin-related complication: a case report

Journal of Medical Case Reports, 2010
Introduction Legionella pneumonia can appear with different levels of severity and it can often present with complications such as acute respiratory distress syndrome.
Piro Roberto, Cavazza Alberto, Castagnetti Claudia, Menzella Francesco, Facciolongo Nicola, Carbonelli Cristiano, Zucchi Luigi   +6 more
doaj   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Troponin T level in children with acute chest diseases and respiratory distress

Egyptian Journal of Chest Disease and Tuberculosis, 2020
Background Respiratory distress owing to pulmonary causes is the most common cause of visits to the pediatric emergency departments. Cardiac complications are reported to occur in acute respiratory tract diseases such as myocarditis, pericarditis, heart ...
Laila A.G Hegazy, Hania N Mossad, Nancy S Wahba, Sally R Ishak   +3 more
doaj   +1 more source

Extreme obesity is a strong predictor for in-hospital mortality and the prevalence of long-COVID in severe COVID-19 patients with acute respiratory distress syndrome [PDF]

, 2022
Lars Heubner, Paul Leon Petrick, Andreas Güldner, Lea Bartels, Maximillian Ragaller, Martin Mirus, Axel Rand, Oliver Tiebel, Jan Beyer‐Westendorf, M Rößler, Jochen Schmitt, Thea Koch, Peter Spieth   +12 more
openalex   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

Monocyte-to-lymphocyte ratio is associated with 28-day mortality in patients with acute respiratory distress syndrome: a retrospective study [PDF]

, 2021
Lijuan Yang, Chang Gao, Fengyuan Li, Ling Yang, Jiahao Chen, Shiqi Guo, Ying He, Qiang Guo   +7 more
openalex   +1 more source

Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression

Advanced Science, EarlyView.
Red blood cell (RBC)‐derived exosomal miR‐93‐5p is elevated in lung cancer patients and correlates with poor outcomes. Exosomal miR‐93‐5p suppresses PTEN in cancer cells, enhancing proliferation, migration, and invasion. In mouse models, therapeutic inhibition with ASO‐miR‐93 5p reduces tumor growth, highlighting a bidirectional tumor‐RBC‐tumor axis ...
Ning Li, Pushpa Dhilipkannah, Van K Holden, Ashutosh Sachdeva, Feng Jiang   +4 more
wiley   +1 more source