Results 151 to 160 of about 3,409,620 (281)

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Genetic Regulation of Protein Biomarkers in Pediatric Acute Respiratory Distress Syndrome. [PDF]

Crit Care Explor
Helman G, Feng R, Motelow JE, Yehya N.
europepmc   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Acute Respiratory Distress Syndrome in Hospital-Acquired/Ventilator-Associated Pneumonia. [PDF]

Med Sci (Basel)
Calabretta D, Accetturo C, Torres A.
europepmc   +1 more source

Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs

Veterinary Record, EarlyView.
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin, Ariadne Rein, Isabella de Almeida Fabris, Beatriz Gasser, Luiz Paulo Nogueira Aires, Bruna Bressianini Lima, Daniele Azevedo Gandra, Daniela Gomes da Silva, Ricardo Andrés Ramirez Uscategui, Gabriela Castro Lopes Evangelista, Marcus Antônio Rossi Feliciano, Paola Castro Moraes   +11 more
wiley   +1 more source

Pathogenesis of acute lung injury: Clinical studies

, 2019
Over the past three decades, experimental studies have contributed substantially to an increased understanding of the pathogenesis of acute lung injury (ALI) and its extreme manifestation, the acute respiratory distress syndrome (ARDS).
Creagh-Brown, Benedict C., Evans, Timothy W.   +1 more
core  

Impact of a Structured Caesarean Reduction Strategy on Perinatal Outcomes: A Retrospective Ecological Time‐Trend Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the long‐term impact of a structured, multidisciplinary CS reduction strategy in a high‐complexity Italian hospital. Design Retrospective ecological time‐trend study. Setting Tertiary obstetric care Italian centre. Sample 28 577 deliveries, ≥ 22 weeks' gestation, from 2014 to 2024 were analysed.
Stefania Fieni, Giovanni Morganelli, Gabriella Maria Celora, Biancamaria Mastrandrea, Tullio Ghi   +4 more
wiley   +1 more source

Biomarkers for Pediatric Acute Respiratory Distress Syndrome: A Systematic Review. [PDF]

J Inflamm Res
Yang F, Zou J, Zheng L, Zeng C, Xu H, Yang J.   +5 more
europepmc   +1 more source

Guillain-Barré Syndrome Complicated by Severe Acute Respiratory Distress Syndrome: A Case Report

Yao Sun, Huiying Zhao, Youzhong An Department of Critical Care Medicine, Peking University People’s Hospital, Beijing, People’s Republic of ChinaCorrespondence: Huiying Zhao; Youzhong An, Peking University People’s Hospital, No. 11 Xizhimen South Street,
An Y, Sun Y, Zhao H
core  

Comparison of Definitions of Severe Maternal Morbidity: A National Cohort Study Using Administrative Data

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To understand agreement between definitions of severe maternal morbidity (SMM), the reasons for disagreement and the impact the outcome definition may have on the measurement of ethnic and socioeconomic inequalities. Design A national cohort study using administrative data. Setting The English National Health Service.
Ian Henderson, Dorothea Geddes‐Barton, Raph Goldacre, Marian Knight   +3 more
wiley   +1 more source