Results 211 to 220 of about 401,782 (243)

Millikelvin Intracellular Nanothermometry with Nanodiamonds

Advanced Science, EarlyView.
Nanothermometry in living cells is crucial for understanding heat diffusion and advancing cellular biology and drug discovery. Previous studies have reported controversial intracellular temperature variations. Using nanodiamond nanothermometry in macrophages, it is found that, in such experimental setting, apparent temperature changes are actually due ...
Maabur Sow, Jacky Mohnani, Genko Genov, Raphael Klevesath, Elisabeth Mayerhoefer, Yuliya Mindarava, Rémi Blinder, Soumen Mandal, Fabien Clivaz, Raúl B. Gonzalez, Daniel Tews, Christian Laube, Wolfgang Knolle, Amelie Jerlitschka, Farid Mahfoud, Oleg Rezinkin, Mateja Prslja, Yingke Wu, Pamela Fischer‐Posovszky, Martin B. Plenio, Susana F. Huelga, Tanja Weil, Anke Krueger, Gavin W. Morley, Oliver A. Williams, Steffen Stenger, Fedor Jelezko   +26 more
wiley   +1 more source

Pressure-controlled ventilation versus volume-controlled ventilation for adult patients with acute respiratory failure: A systematic review and meta-analysis. [PDF]

Medicine (Baltimore)
Suntrawanichakul S, Ngamjarus C, Sawanyawisuth K, Khamsai S.   +3 more
europepmc   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Ventilation-induced acute kidney injury in acute respiratory failure: Do PEEP levels matter? [PDF]

Crit Care
Benites MH, Suarez-Sipmann F, Kattan E, Cruces P, Retamal J.   +4 more
europepmc   +1 more source

Diversity and Ecological Potentials of Marine Viruses Inhabiting Continental Shelf Seas

Advanced Science, EarlyView.
To the best of the knowledge, this study provides the largest viral genome dataset from a continental shelf sea. It reveals that over half of vOTUs are novel, highlighting the remarkable viral novelty in the eastern continental shelf seas of China (ECSSC).
Xiaoyue Guo, Yantao Liang, Chen Gao, Hao Yu, Meiwen Wang, Hongbing Shao, Yeqing Yang, David Paez‐Espino, Andrew McMinn, Min Wang   +9 more
wiley   +1 more source

High-flow nasal Oxygen with or without alternating helmet Non-invasive ventilation for Oxygenation sUpport in acute Respiratory failure (HONOUR): a protocol for a pilot randomised controlled trial. [PDF]

BMJ Open
Angriman F, Ferreyro BL, Rochwerg B, Sklar M, Adhikari N, Bagshaw SM, Brochard L, Cuthbertson B, Del Sorbo L, Fowler R, Geagea A, Granton JT, Mehta S, Munshi L, Muscedere J, Nardi J, Parhar K, Pinto RL, Piquette D, Seely A, Slessarev M, Tobin S, Scales DC, Ferguson ND, HONOUR Investigators and the Canadian Critical Care Trials Group.   +24 more
europepmc   +1 more source

An elderly woman with acute respiratory failure and diffuse pulmonary changes

Chun Ian Soo, Wai Yie Leong, Nadia Fareeda Muhammad Gowdh, Leng Cheng Sia, Vijayan Munusamy, C. K. Wong, Nazarina Abdul Rahman   +6 more
openalex   +1 more source

Cancer Biology of GSPT1: Mechanisms and Targeted Therapy Opportunities of Molecular Glue Degraders

Advanced Science, EarlyView.
This review systemically summarizes the structure, expression, regulatory networks, and isoform‐specific signaling of GSPT1 in cancers. According to the integration of GSPT1 targeted therapies, current challenges of GSPT1 targeted therapies are further analyzed, and provide therapeutic opportunities for the application of GSPT1 degraders in precision ...
Qiqi Lin, Wenjing Liu, Wenjia Lu, Monong Zhao, Lin Cao, Zhiyu Li, Jubo Wang, Xi Xu, Hongxi Wu   +8 more
wiley   +1 more source