Results 311 to 320 of about 1,201,249 (376)

High-frequency percussive ventilation in acute respiratory failure. [PDF]

ERJ Open Res
Bruni A, Neri G, Cammarota G, Bosco V, Biamonte E, Troisi L, Boscolo A, Navalesi P, Longhini F, Garofalo E.   +9 more
europepmc   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Novel lung imaging techniques: new experimental insights in acute respiratory failure. [PDF]

Intensive Care Med Exp
Pellegrini M, Cereda M.
europepmc   +1 more source

Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2‐Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction

Advanced Science, EarlyView.
SCAP/ARDS patients show reduced unsaturated fatty acids (UFAs) but higher PARK7 and lactate in plasma. PARK7 correlates positively with lactate and negatively with UFAs. Pulmonary endothelial cell multi‐omics show FADS1/2 downregulation and impaired PUFA metabolism. Lactate boosts PARK7 via H3K14 lactylation, and PARK7 then restores FADS1/2.
Jian Xu, Yuhan Wang, Weiqi Mao, Tianchang Wei, Yufan Li, Juan Song, Cuiping Zhang, Xiaoyan Chen, Cuicui Chen, Qingyuan Xu, Xu Wu, Yuanlin Song   +11 more
wiley   +1 more source

Acute Respiratory Failure in Children: A Clinical Update on Diagnosis. [PDF]

Children (Basel)
Panetti B, Bucci I, Di Ludovico A, Pellegrino GM, Di Filippo P, Di Pillo S, Chiarelli F, Attanasi M, Sferrazza Papa GF.   +8 more
europepmc   +1 more source

Utilizing Proteolytic‐Resistant Nano‐Short Peptide Based on Naphthyl Tail‐Anchored to Combat Bacterial Infections

Advanced Science, EarlyView.
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan, Yinfeng Lyu, Yi Liu, Jianping Ren, Yue Zhao, Licong Zhang, Anshan Shan   +6 more
wiley   +1 more source

SELENON-related myopathy as a cause of acute respiratory failure in middle age: a case report. [PDF]

J Med Case Rep
Risi B, Caria F, Damioli S, Labella B, Lanzi G, Bugatti M, Baronchelli C, Bertella E, Giovanelli G, Ferullo L, Olivieri E, Poli L, Padovani A, Filosto M.   +13 more
europepmc   +1 more source

Prediction of Lung Cancer Metastasis Risk Based on Single‐Cell Metabolic Profiling of Circulating Tumor Cells

Advanced Science, EarlyView.
A self‐developed CTC sorting and capture platform enabled single‐cell metabolomics of patient/animal CTCs, revealing brain/bone metastasis‐specific metabolic signatures. A classification model developed from these signatures predicted lung cancer metastasis risk, outperforming traditional markers and total CTC counts (AUCs:89 brain = 0.74; bone = 0.92).
Yang Xu, Xuesen Hu, Yuan Yuan, Wenwen Liu, Jian Wang, Chunhui Yang, Xianzhe Shi, Wangshu Qin, Liliang Wen, Manqing Lin, Yinuo Jin, Wei Wang, Chunxiu Hu, Guowang Xu, Qi Wang   +14 more
wiley   +1 more source

Association between the triglyceride glucose index and the risk of acute respiratory failure in patients with acute pancreatitis. [PDF]

BMC Gastroenterol
Lv J, Zhou Y, Tao C, Cai Y, Yang H, Xu J, Chen J, Sun R.   +7 more
europepmc   +1 more source