Results 71 to 80 of about 704,383 (285)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Predictors and outcomes of acute respiratory failure in hospitalised patients with acute pancreatitis [PDF]

, 2020
Mahesh Gajendran, Bharat Prakash, Abhilash Perisetti, Chandraprakash Umapathy, Vineet Gupta, Laura C. Collins, Prashanth Rawla, Priyadarshini Loganathan, Alok Dwivedi, Christopher Dodoo, Fortune Unegbu, Dan Schuller, Hemant Goyal, Shreyas Saligram   +13 more
openalex   +1 more source

Biosupercapacitors for Human‐Powered Electronics

Advanced Functional Materials, EarlyView.
Biosupercapacitors are emerging as biocompatible and integrative energy systems for next‐generation bioelectronics, offering rapid charge–discharge performance and mechanical adaptability. This review systematically categorizes their applications from external to organ‐level systems and highlights their multifunctional roles in sensing, actuation, and ...
Suhyeon Kim, Seungho Baek, Woojung Jung, Hayeon Bae, Junyoung Mun, Yong Ho Kim, Sunkook Kim, Jung Ho Kim   +7 more
wiley   +1 more source

A Bespoke Programmable Interpenetrating Elastomer Network Composite Laryngeal Stent for Expedited Paediatric Laryngotracheal Reconstruction

Advanced Functional Materials, EarlyView.
A programmable interpenetrating double‐network architecture, created via 3D‐TIPS printing and resin infusion, synergistically combines thermoplastic and thermosetting elastomers to balance structural rigidity and surface softness—crucial for paediatric laryngeal stents.
Elizabeth F. Maughan, Lei Wu, Dong Zhang, Linxiao Wu, Graca Ferreira Vaz Pinto Mendes, Wanqiao J. Tu, Heping Ma, Toby J. Proctor, Colin R. Butler, Thomas Kjærgaard, Mark W. Lowdell, Martin A. Birchall, Robert E. Hynds, Richard Hewitt, Wenhui Song   +14 more
wiley   +1 more source

Boussignac CPAP in acute respiratory failure

Italian Journal of Medicine, 2013
Introduction: The application of continuous positive airway pressure (CPAP) is one of the most important therapeutic interventions used in patients with acute respiratory failure (ARF) secondary to acute cardiogenic pulmonary edema (ACPE).
Federico Lari, Francesco Savelli, Fabrizio Giostra, Gianpaolo Bragagni, Nicola Di Battista   +4 more
doaj   +1 more source

Severe exacerbations and acute respiratory failure in COPD [PDF]

, 2021
Roy T.M. Sprooten
openalex   +1 more source

Critical Care Ultrasonography and Its Application for COVID-19 [PDF]

, 2020
Ultrasound has developed as an invaluable tool in diagnosis and proper management in the intensive care unit (ICU). Application of critical care ultrasonography is quite distinct from the routine comprehensive diagnostic ultrasound exam, because the ...
Chong, MD, Weelic, Hai, MD, Yang, Liu, MD, Ji-Bin, Liu, MD, Xi, Ma, MD, Bin   +4 more
core   +1 more source

Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? [PDF]

, 2018
Aims: Changes in systolic blood pressure (SBP) during an admission for acute heart failure (AHF), especially those leading to hypotension, have been suggested to increase the risk for adverse outcomes.
Bourge, Robert C., Cleland, John G.F., Cotter, Gad, Davison, Beth A., Edwards, Christopher, Jondeau, Guillaume, Kobrin, Isaac, McMurray, John J.V., Metra, Marco, Milo, Olga, O'Connor, Christopher M., Parker, John D., Rainisio, Maurizio, Senger, Stefanie, Teerlink, John R., Torre-Amione, Guillermo, van Veldhuisen, Dirk J.   +16 more
core   +3 more sources

Functional Materials for Environmental Energy Harvesting in Smart Agriculture via Triboelectric Nanogenerators

Advanced Functional Materials, EarlyView.
This review explores functional and responsive materials for triboelectric nanogenerators (TENGs) in sustainable smart agriculture. It examines how particulate contamination and dirt affect charge transfer and efficiency. Environmental challenges and strategies to enhance durability and responsiveness are outlined, including active functional layers ...
Rafael R. A. Silva, Giulio Fatti, Emanuel Carlos, Guilherme Ferreira, Sumita Goswami, Suman Nandy, Luiz H. C. Mattoso, Elvira Fortunato, Caio G. Otoni, Rodrigo Martins   +9 more
wiley   +1 more source

Noninvasive positive pressure ventilation in acute respiratory failure due to COPD vs other causes: Effectiveness and predictors of failure in a respiratory ICU in North India

International Journal of COPD, 2008
Ritesh Agarwal, Rajesh Gupta, Ashutosh N Aggarwal, Dheeraj GuptaDepartment of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaObjectives: To determine the effectiveness of noninvasive positive pressure ...
Ritesh Agarwal, Rajesh Gupta, Ashutosh N Aggarwal, Dheeraj Gupta   +3 more
doaj