Results 231 to 240 of about 1,512,759 (352)

A Systematic Review of the Markers of Severity in Acute Respiratory Infections to Inform Primary Care Surveillance. [PDF]

Influenza Other Respir Viruses
Elson WH, Forbes A, Jamie G, Wimalaratna R, Morbey R, Hobbs FDR, de Lusignan S, Bernal JL.   +7 more
europepmc   +1 more source

Optimal antimicrobial duration for common bacterial infections [PDF]

, 2019
Daveson, Kathryn, Del Mar, Christopher B., Wilson, Heather L.   +2 more
core   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Acute Respiratory Infections Of Children

Indian Journal of Community Medicine, 1986
Steinhoff M.C
doaj  

Hospital-Based Investigation of Acute Respiratory Infections in Children Under Five: Epidemiology, Seasonality, and Co-infections. [PDF]

Cureus
Mishra B, Mohapatra D, Panda S, Santra D, Mandal MC, Mamidi P, Dwibedi B, Das RR, Das S, Mohapatra PR, Behera B, Gulla KM, Som TK.   +12 more
europepmc   +1 more source

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

Advanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji‐Joon Song, Meehyein Kim, Sangyong Jon   +6 more
wiley   +1 more source

Acute respiratory infections in children and adolescents with acute lymphoblastic leukemia

Cancer, 2016
H. Hakim, Ronald H Dallas, Yinmei Zhou, Dequing Pei, Cheng Cheng, P. Flynn, C. Pui, S. Jeha   +7 more
semanticscholar   +1 more source

DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition

Advanced Science, EarlyView.
A honeycomb‐shaped DNA nanostructure is introduced that organizes nanobodies or aptamers into trimeric clusters mirroring the native hemagglutinin arrangement on influenza viruses. This geometry‐matched multivalency enhances binding avidity by up to 1000‐fold, resulting in robust, broad‐spectrum viral neutralization and a 30–55% improvement in host ...
Saurabh Umrao, Abhisek Dwivedy, Dhanush Gandavadi, Chi Chen, Lifeng Zhou, Jinwei Duan, Vineetha Mareddy, Ying Fang, Xing Wang   +8 more
wiley   +1 more source

Clinical Experience with Inosine Pranobex in Pediatric Acute Respiratory Infections with Comorbidities: A Case Series from a Specialised Centre. [PDF]

Pediatr Rep
Kunč P, Fábry J, Ištvánková K, Péčová R, Jeseňák M.   +4 more
europepmc   +1 more source