Results 51 to 60 of about 1,512,759 (352)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Clinical and economic efficacy of ribosomal therapy in children in the prevention of acute respiratory infections

Медицинский совет, 2015
The article tells about the problem of acute respiratory infections in preschool children. Pharmacoeconomic efficacy of ribosomal immunomodulatory therapy for the prevention of acute respiratory infections is evaluated.
A. L. Zaplatnikov, I. N. Dyakov, A .A. Girina, N. A. Korovina, A. V. Suzdalenkov, V. I. Svintsitskaya   +5 more
doaj   +1 more source

Genetic relatedness of infecting and reinfecting respiratory syncytial virus strains identified in a birth cohort from rural Kenya [PDF]

, 2012
Background: Respiratory syncytial virus (RSV) reinfects individuals repeatedly. The extent to which this is a consequence of RSV antigenic diversity is unclear.
Alexander G. Mwihuri, Anderson, Cane, Cane, Cane, Cane, Cane, Charles J. Sande, Charles N. Agoti, Choi, Clayton O. Onyango, Collins, D. James Nokes, Falsey, Falsey, Glezen, Graham F. Medley, Gunson, Hall, Hall, Hall, Henderson, Johnson, Johnson, Melero, Mufson, Mufson, Nair, Nokes, Nokes, Ohuma, Okiro, Parveen, Patricia A. Cane, Peret, Peret, Posada, Sande, Scott, Sullender, Sullender, Tamura, Trento, Trento, Trento, Venter, Waris, White, Xia, Yamaguchi, Zlateva   +50 more
core   +1 more source

The Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment of Severe Acute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-analysis

Journal of Infectious Diseases, 2014
Background. Administration of convalescent plasma, serum, or hyperimmune immunoglobulin may be of clinical benefit for treatment of severe acute respiratory infections (SARIs) of viral etiology.
John Mair-Jenkins, M. Saavedra-Campos, J. Baillie, P. Cleary, F. Khaw, W. Lim, Sophia Makki, K. Rooney, J. Nguyen-Van-Tam, C. Beck, A. Mateus, S. Reuter, Jinho Shin, Xiaolin Xu, D. Pereyaslov, I. Papieva, A. Tegnell, H. Englund, Åsa Elfving, R. Cox, K. Mohn, Yingjie Feng Jenkins   +21 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

SYMPTOMATIC THERAPY OF COUGH DURING SEASONAL INCREASE OF ACUTE RESPIRATORY INFECTIONS PREVALENCE

Вопросы современной педиатрии, 2014
Cough is the main symptom of the respiratory tract disorders. Mostly it occurs in viral, bacterial and mixed (viral and bacterial) respiratory tract infections.
K. S. Volkov, L. S. Namazova-Baranova, N. I. Voznesenskaya, V. A. Barannik, K. E. Efendieva   +4 more
doaj   +1 more source

Standard Index of Air Pollutant, Meteorology Factor and Acute Respiratory Infections Occurrence in Pekanbaru [PDF]

, 2017
This study aims to know the relationship between standard index of air pollutant and meteorology factor with acute respiratory infections occurrence in Pekanbaru city. This ecological study involved community with acute respiratory infections. There is a
Irawan, A. (Angki), Sukandarrumidi, S. (Sukandarrumidi), Sutomo, A. H. (Adi)   +2 more
core  

Emerging viral respiratory tract infections—environmental risk factors and transmission [PDF]

, 2014
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Charrel, Remi N., Gautret, Philippe, Gray, Gregory C., Memish, Ziad A., Odezulu, Nnanyelugo G., Zumla, Alimuddin   +6 more
core   +1 more source

Risk factors of acute respiratory infections among under five children attending public hospitals in southern Tigray, Ethiopia, 2016/2017

BMC Pediatrics, 2019
BackgroundAcute Respiratory infection accounts for 94,037000 disability adjusted life years and 1.9 million deaths worldwide. Acute respiratory infections is the most common causes of under-five illness and mortality.
Sielu Alemayehu, Kalayou Kidanu, Tensay Kahsay, M. Kassa   +3 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source