Results 191 to 200 of about 340,522 (264)

Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis

Interdisciplinary Medicine, EarlyView.
Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar, Sunil Kumar Singh, Piush Srivastava, Sowdhamini Mahendiran, Rakesh Sathish Nair, Harsh Vyas, Saket Jha, Niraj Nag, Navin Viswakarma, Hitesh Kapoor, Swathi Suresh, Periannan Sethupathi, Sang‐Ging Ong, Jerrold S. Levine, Suman Setty, Mathayan Manikannan, Bellur S. Prabhakar, Basabi Rana, Ajay Rana   +18 more
wiley   +1 more source

The respiratory microbiome influences the occurrence of respiratory diseases in children. [PDF]

Front Pediatr
Zheng K, Zhou SH, Liao S, Mu J, Han ZB, Wang B.   +5 more
europepmc   +1 more source

[Acute lower respiratory viral infections].

Revista chilena de pediatria, 1992
openaire   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Encephalitis With Cerebrospinal Fluid Polymerase Chain Reaction (PCR) Positivity and Normal Neuroimaging: A Case Report. [PDF]

Cureus
Dias G, Franco AI, Santos MG, Graveto C, Araújo A.   +4 more
europepmc   +1 more source

A Novel Air‐Liquid Interface Exposure System for Continuous Gas Exposure of Airway Epithelial Cells: Exposure of NO2 With Viral Co‐Challenge

Journal of Applied Toxicology, EarlyView.
ABSTRACT Most in vitro toxicological research investigating the effects of inhaled compounds employ short‐term exposures of a couple of hours, or repeated, intermittent exposures for a limited number of days with exposure free periods, whereas in reality, we are continuously exposed, albeit to variable concentrations.
Marcia M. Oldenburger, Evert Duistermaat, Pieter S. Hiemstra, Flemming R. Cassee, Yvonne C. M. Staal   +4 more
wiley   +1 more source

Hypertransaminasemia Is a Marker of Severity in Children Hospitalized for Influenza. [PDF]

Influenza Other Respir Viruses
Poeta M, Moracas C, Venturini E, Sgubbi S, Valentino MS, Folgori L, Petrarca L, Cafagno C, Maglione M, Cascone A, Colomba C, Romero A, Midulla F, Indolfi G, Giacomet V, Licari A, Galli L, Guarino A.   +17 more
europepmc   +1 more source

Utility of a Combined Diagnostic and Severity Scoring System Based on Complete Blood Count and Derived Immune‐Inflammatory Indicators in Children With Mycoplasma pneumoniae Pneumonia

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a simple, low‐cost scoring system using routine complete blood count (CBC) and derived immune‐inflammatory indicators (LYM%, PLT, PCT, and PLT × LYM) for early diagnosis of Mycoplasma pneumoniae pneumonia (MPP) in 1662 children. Age‐stratified analysis confirmed that key indicators remained significantly higher in the pneumonia ...
Quan Liu, Li Wei, Liang Wang, Xing‐Mei Zhu, Hai‐Feng Wang, Ling Ge   +5 more
wiley   +1 more source

The epidemiology of SARS-CoV-2, Influenza, and Respiratory Syncytial Virus circulation among adult patients with acute respiratory illness in Kampala Metropolitan Area in Uganda. [PDF]

PLoS One
Arinaitwe J, Bakamutumaho B, Mugenyi L, Kiwanuka N, Alupo P, Kawuma AN, Ndahura K, Sekimpi M, Akurut E, Muttamba W, Joloba M, Ocan M, Wampande E, Kyosiimire Lugemwa J, Nakibuuka J, Lusiba J, Okia J, Owachi D, Byakika-Kibwika P, Kirenga B.   +19 more
europepmc   +1 more source