Results 91 to 100 of about 443,940 (300)

Nutraceuticals in the complex therapy of asthenic syndrome after acute respiratory viral infection

open access: yesКлинический разбор в общей медицине
Asthenia/asthenic syndrome is present in the clinical picture of a large number of diseases and conditions, and, accordingly, the causes of asthenia are diverse.
Dmitry I. Trukhan   +4 more
doaj   +1 more source

Improved detection of respiratory viruses in pediatric outpatients with acute respiratory illness by real-time PCR using nasopharyngeal flocked swabs [PDF]

open access: yes, 1999
Detection of respiratory viruses by realtime multiplexed PCR (M-PCR) and of RSV by M-PCR and immunofluorescence(IF) was evaluated using specimens collected by nasopharyngeal flocked swab(NFS) and nasal wash(NW).
Munywoki, Patrick   +5 more
core   +2 more sources

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

Non-specific prevention of infections in children

open access: yesМедицинский совет, 2016
ARVI (acute respiratory viral infections, also often called ARD - acute respiratory disease) is a group of diseases that are similar in character and mostly characterized by a pathology of the respiratory system.
N. L. Kunelskaya   +5 more
doaj   +1 more source

The causes and consequences of seasonal variation in COPD exacerbations [PDF]

open access: yes, 2014
Gavin C Donaldson, Jadwiga A Wedzicha Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, UK Abstract: The time of year when patients experience exacerbations of chronic obstructive pulmonary disease is a much ...
Donaldson, G, Wedzicha, J
core   +2 more sources

RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis

open access: yesAdvanced Science, EarlyView.
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao   +28 more
wiley   +1 more source

VIRAL ETIOLOGY OF ACUTE RESPIRATORY INFECTIONS IN PEDIATRIC PATIENTS IN LEBANON

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2019
 Background: Acute respiratory infections (ARI) are the leading cause of death worldwide especially among children. The majority of these infections in children are of viral etiology. In this study, we evaluated the incidence of viral ARI among children in Lebanon.
Masoud, Khaldoun   +6 more
openaire   +4 more sources

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

open access: yesAdvanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang   +17 more
wiley   +1 more source

The diagnosis and treatment of elderly patients with acute exacerbation of chronic obstructive pulmonary disease and chronic bronchitis. [PDF]

open access: yes, 2010
The syndrome of chronic obstructive pulmonary disease (COPD) consists of chronic bronchitis (CB), bronchiectasis, emphysema, and reversible airway disease that combine uniquely in an individual patient.
Albertson, Timothy E   +2 more
core  

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

open access: yesAdvanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun   +11 more
wiley   +1 more source

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