Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2015 Purpose : explore the functional status and quality of life of students after acute viral infectious diseases. Material : a total of 25 students aged 19-22 years after the acute respiratory viral infections and 20 healthy people.
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LAG-3 Contribution to T Cell Downmodulation during Acute Respiratory Viral Infections. [PDF]
Viruses, 2023 Rodríguez-Guilarte L +3 more
europepmc +1 more source
PB2025 ACUTE RESPIRATORY VIRAL INFECTIONS IN CHILDREN WITH ACUTE LEUKEMIA
HemaSphere, 2019 Background:Although major advances have been made in the treatment of leukemia in recent years, infections that develop during treatment still cause significant morbidity and mortality in children with acute leukemias. The general approach in febrile neutropenia is to initiate empirical antibacterial therapy for possible bacterial infections and to add
Ö. Tüfekçi +5 more
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GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
A systematic review and meta‑analysis of Arbidol therapy for acute respiratory viral infections: A potential treatment for COVID‑19. [PDF]
Exp Ther Med, 2022 Feng T +6 more
europepmc +1 more source
Seasonality and selective trends in viral acute respiratory tract infections
Medical Hypotheses, 2016 Influenza A and B, and many unrelated viruses including rhinovirus, RSV, adenovirus, metapneumovirus and coronavirus share the same seasonality, since these viral acute respiratory tract infections (vARIs) are much more common in winter than summer.
openaire +2 more sources
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
Advanced Science, EarlyView.ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Oncolytic Probiotics with Molecular Pili for Solid Tumor Therapy
Advanced Science, EarlyView.This study identifies Lactobacillus rhamnosus as an intrinsic oncolytic agent that triggers tumor metabolic collapse via calcium‐dependent ROS bursts. By chemically anchoring collagen‐targeting “molecular pili” to the bacterial surface, the engineered non‐transgenic probiotic (LR@MP) achieves targeted colonization and potent solid tumor suppression ...
Haodong Ge +14 more
wiley +1 more source
Changes in the pattern and disease burden of acute respiratory viral infections before and during the COVID-19 pandemic. [PDF]
Osong Public Health Res Perspect, 2022 Park C +5 more
europepmc +1 more source
A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat
Advanced Science, EarlyView.An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su +10 more
wiley +1 more source