Results 41 to 50 of about 443,940 (300)

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes [PDF]

open access: yes, 2012
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs.
A. Vabret   +61 more
core   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Colostral immunity as an analytical factor in predicting the development of acute respiratory viral infections in calves

open access: yesВетеринария сегодня, 2021
To reduce the incidence of acute respiratory viral infections in cattle, routine vaccination of mother cows is carried out. There is a direct dependence of the passive immunity level in calves on the vaccination efficacy in cows.
E. N. Shilova   +3 more
doaj   +1 more source

Epidemiological features and ways of improving prevention of acute respiratory viral infections [PDF]

open access: yes, 2017
Acute respiratory viral infections for many years remain relevant problems of the health care ...
Goncharova, T.M., Siver, M.F.
core  

Viral Infection in Adults with Severe Acute Respiratory Infection in Colombia

open access: yesPLOS ONE, 2015
To identify the viral aetiology in adult patients with severe acute respiratory infection (SARI) admitted to sentinel surveillance institutions in Bogotá in 2012.A cross-sectional study was conducted in which microarray molecular techniques for viral identification were used on nasopharyngeal samples of adult patients submitted to the surveillance ...
Yuly Andrea Remolina   +7 more
openaire   +4 more sources

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Performance of diagnostic tests to detect respiratory viruses in older adults. [PDF]

open access: yes, 2010
The performance of 4 laboratory methods for diagnosis of viral respiratory tract infections (RTI) in older adults was evaluated. Seventy-four nasopharyngeal (NP) swab specimens were obtained from 60 patients with RTI at a long-term care facility over 2 ...
Caram, Lauren B   +7 more
core  

A systematic review of emerging respiratory viruses at the Hajj and possible coinfection with Streptococcus pneumoniae [PDF]

open access: yes, 2018
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A.   +2 more
core   +1 more source

Pathophysiology of Clinical Symptoms in Acute Viral Respiratory Tract Infections [PDF]

open access: yes, 2015
In this article we discuss the pathophysiology of common symptoms of acute viral respiratory infections (e.g., sneezing, nasal discharge, sore throat, cough, muscle pains, malaise, and mood changes). Since clinical symptoms are not sufficient to determine the etiology of viral respiratory tract infections, we believe that the host defense mechanisms ...
Kuchar, E.   +3 more
openaire   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

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