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Rheumatic Fever (ARF) is an autoimmune, nonsuppurative sequela of pharyngeal infection caused by Group A beta-hemolytic Streptococcus (GAS). It remains a significant cause of cardiovascular morbidity in developing countries. This article reviews the etiology, pathogenesis, clinical stages, types, diagnostic methods (laboratory and instrumental ...
Chowdhury MDS +3 more
europepmc +6 more sources
Genetic susceptibility to acute rheumatic fever: a systematic review and meta-analysis of twin studies. [PDF]
BackgroundAcute rheumatic fever is considered to be a heritable condition, but the magnitude of the genetic effect is unknown. The objective of this study was to conduct a systematic review and meta-analysis of twin studies of concordance of acute ...
Mark E Engel +4 more
doaj +5 more sources
Diagnostic test accuracy of simplified algorithms for diagnosing acute rheumatic fever: a systematic review [PDF]
Background Rheumatic heart disease, the long-term sequel to acute rheumatic fever, remains a prevalent public health problem in Africa and other low to middle-income regions of the world.
Rui Providencia +10 more
doaj +2 more sources
Revisiting The Value of Anti-streptolysin O Titer in Children with Rheumatic Fever [PDF]
Background: Acute rheumatic fever and rheumatic heart disease are the significant non-suppurative late sequelae of group A beta hemolytic streptococcal infection.
Mohamed S. Eid +4 more
doaj +1 more source
The rise and fall of acute rheumatic fever and rheumatic heart disease: a mini review
Introduction The incidences of acute rheumatic fever (ARF) and rheumatic heart disease (RHD), which were leading causes of death in children in the 1920s, have decreased substantially.
Yunmei Liang +4 more
semanticscholar +1 more source
Group A Streptococcus (GAS) causes superficial and invasive infections and immune mediated post-infectious sequalae (including acute rheumatic fever/rheumatic heart disease).
T. Auala +3 more
semanticscholar +1 more source
Risk factors for acute rheumatic fever: A case-control study
Summary Background Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) remain an inequitable cause of avoidable suffering and early death in many countries, including among Indigenous Māori and Pacific populations in New Zealand.
M. Baker +15 more
semanticscholar +1 more source
Acute rheumatic fever and rheumatic heart disease in children and adolescents in Victoria, Australia
To describe the epidemiology and clinical profile of children and adolescents with acute rheumatic fever (ARF) and rheumatic heart disease (RHD) in Victoria, Australia.
Daniel E. Lindholm +11 more
semanticscholar +1 more source
Introduction Acute rheumatic fever (ARF) is usually considered a consequence of group A streptococcus (GAS) pharyngitis, with GAS skin infections not considered a major trigger.
J. Oliver +8 more
semanticscholar +1 more source

