Results 151 to 160 of about 186,510 (285)

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang   +3 more
wiley   +1 more source

Immune endotypes in tuberculosis: Keys to decoding disease complexity

open access: yesJournal of Internal Medicine, Volume 299, Issue 6, Page 670-693, June 2026.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor   +4 more
wiley   +1 more source

Trimethoprim/Sulfamethoxazole‐Induced Systemic Toxic Epidermal Necrolysis Syndrome: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Trimethoprim/sulfamethoxazole can induce life‐threatening toxic epidermal necrolysis. Early recognition, immediate drug cessation, and multidisciplinary supportive care are critical. Even with aggressive therapy, mortality remains high, and SCORTEN score aids in prognostication.
Qing Wang, Litong Chen, Wen Ye
wiley   +1 more source

Severe Adult HLH/MAS With SPTCL‐Like Panniculitis: A Phenotype‐Guided, Resource‐Adapted Therapeutic Strategy Without Cytotoxic Therapy

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
Graphical abstract illustrating the phenotype‐guided therapeutic approach in severe adult HLH/MAS with SPTCL‐like panniculitis, demonstrating clinical and biochemical response following sequential treatment with therapeutic plasma exchange, intravenous immunoglobulin, and cyclosporine.
Hatem Mousa Taha   +2 more
wiley   +1 more source

Lingual Dyskinesia as the Presenting Feature of Acquired Demyelinating Syndrome: A Case Report and Review of Differential Diagnoses

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Briana Davis   +3 more
wiley   +1 more source

Rare Manifestation of Sjogren's Syndrome: Renal Tubular Acidosis‐Induced Hypokalemic Paralysis—A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Sjogren's syndrome (SS) is an autoimmune disorder characterized by inflammation of exocrine glands, often presenting with symptoms such as dry eyes and mouth. Although less common, renal involvement can lead to serious complications like hypokalemic paralysis.
Premendra Vimal   +3 more
wiley   +1 more source

Myocarditis Following Invasive Group A Streptococcus Infection: Important Differential Diagnostic Distinctions

open access: yesCase Reports in Infectious Diseases
Nonrheumatic streptococcal pharyngitis−associated myocarditis presents as acute myocarditis within days of Group A Streptococcus pharyngitis, typically resolving with antibiotics and minimal sequelae.
Jonathan M. Oxman   +3 more
doaj   +1 more source

A Record Study Cardiovascular Diseases Admited in Hospitals Inj Jakarta [PDF]

open access: yes, 1976
Dalam rangka mempelajari epidemiology penyakit cardiovascular sebagai langkah pertama telah dilakukan pencatatan mengenai penderita-penderita penyakit cardiovascular untuk periode tahun 1970 sampai dengan tahun 1973 pada 6 rumah sakit di Jakarta yaitu R ...
S, K. D. (Kartari)   +1 more
core  

Acquired Angioedema Associated With Systemic Lupus Erythematosus Presenting as Acute Abdomen: A Case Report

open access: yesJournal of General and Family Medicine, Volume 27, Issue 3, May 2026.
ABSTRACT Acquired angioedema (AAE) due to C1 inhibitor deficiency can present as acute abdomen. A 24‐year‐old woman developed severe abdominal pain and bowel wall edema initially suggestive of hereditary angioedema, but genetic testing excluded it. She later manifested fever, arthritis, rash, and serological abnormalities consistent with systemic lupus
Seiji Shiota   +2 more
wiley   +1 more source

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