Results 91 to 100 of about 14,468 (231)

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Acute rhinosinusitis during upper respiratory infection in children [PDF]

, 2005
Acute rhinosinusitis is estimated to be one of the most common diseases in childhood. Still, the diagnostics and clinical relevance of this disease are controversial.
Kristo, A. (Aila)
core   +1 more source

Rhinosinusitis: classification, epidemiology, etiology and treatment

Медицинский совет, 2016
The incidence of acute and chronic rhinosinusitis among children and adult population is growing worldwide. The article tells about the results of recent research on the prevalence of rhinosinusitis, classification, etiological aspects, major therapeutic
A. A. Krivopalov
doaj   +1 more source

Acute Exacerbations of Chronic Rhinosinusitis

Current Allergy and Asthma Reports
Abstract Purpose of Review We aim to highlight recent advancements on the evolving chronic rhinosinusitis (CRS) phenotype: acute exacerbations of chronic rhinosinusitis (AECRS). We focused on studies that expanded the current understanding of its pathophysiology, patient characteristics, and ...
Frederick, Robert M., Lam, Kent, Han, Joseph K.   +2 more
openaire   +2 more sources

Exhaled Volatile Organic Compounds Identify Allergic Patients Among Individuals With Chronic Rhinitis

Allergy, EarlyView.
Exhaled decane and nonadecane discriminate allergic (AR + LAR) from non‐allergic (NAR + HC) subjects among individuals with chronic rhinitis. LAR patients display higher levels of exhaled nonadecane than NAR individuals at baseline. Subjects with FeNO≥ 25 ppb have higher levels of exhaled decane, nonanal, and styrene than individuals with FeNO < 25 ppb
Rosa Alba Sola‐Martinez, Laura Zubiaga‐Fernandez, Marta Figuerola, Anyith Cruz‐Amaya, Carlos J. Aranda, Maria J. Torres, Ibon Eguiluz‐Gracia, Carmen Rondon, Teresa De Diego Puente, Almudena Testera‐Montes   +9 more
wiley   +1 more source

CEFDITOREN IN THE TREATMENT OF PURULENT RINOSINUSITIS

Медицинский совет, 2017
Rhinosinusitis is one of the most common human nosologies. Treatment of acute forms of rhinosinusitis should be comprehensive and directed, first of all, to the eradication of the infectious agent, as well as to restore aeration of the sinuses and ...
G. N. Nikiforova, V. M. Svistushkin, D. M. Pshonkina   +2 more
doaj   +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, EarlyView.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama, Jun Miyata, Takao Mochimaru, Ryuta Onozato, Yo Otsu, Hisashi Sasaki, Keeya Sunata, Shinichi Okuzumi, Katsunori Masaki, Hiroki Kabata, Keinosuke Hizuka, Yoshinori Hasegawa, Ryo Konno, Yusuke Kawashima, Makoto Arita, Shigeharu Ueki, Koichi Fukunaga   +16 more
wiley   +1 more source

Acute Rhinosinusitis

, 2005
Akutni rinosinuitis je upala sluznice nosa i paranazalnih sinusa kod koje su prisutni simptomi nosne začepljenosti, pojačane patološke sekrecije iz nosa ili postnazalno niz ždrijelo, pritiska u licu ili glavobolje te smetnji njuha (najmanje 2 od ova ...
Livije Kalogjera, Kalogjera, Livije
core  

The use ofnatural substances in thetreatment of rhinosinusitis in thelight of the EuropeanPosition Paper on Rhinosinusitis and Nasal Polyps 2012

, 2014
Rhinosinusitis is a very common condition of the upper respiratory tract. The disease may be caused by viral, bacterial or fungal infections as well as by allergens or air pollution (e.g. tobacco smoke), with viral infections being the most common cause.
Agnieszka Pławińska, Małgorzata Pachecka, Pławińska, Agnieszka, Pachecka, Małgorzata, Pachecka, Ryszard, Ryszard Pachecka   +5 more
core   +1 more source

Efficacy and Safety of Dupilumab in Chinese Adult Patients With Chronic Rhinosinusitis With Nasal Polyps: A Randomized, Placebo‐Controlled, Phase III Trial

Allergy, EarlyView.
Dupilumab significantly improved nasal polyp score, nasal congestion, olfaction, total symptom score, and disease‐specific quality of life in Chinese patients with uncontrolled CRSwNP. Incidence of treatment‐emergent adverse events was similar between dupilumab and placebo.
Mu Xian, Menglin Wang, Changqing Zhao, Lijia Wan, Yu Xu, Juan Meng, Rui Xu, Xicheng Song, Li Shi, Yucheng Yang, Yan Jiang, Yanzhen Wu, Bethany Ling, Vivian Li, Andrew P. Fontenot, Lacey R. Robinson, Neelam A. Phadke, Chengshuo Wang, Luo Zhang   +18 more
wiley   +1 more source