Results 211 to 220 of about 432,765 (258)

Acute toxicity of malonaldehyde

Toxicology and Applied Pharmacology, 1965
Abstract The median lethal dose (LD 50 ) of malonaldehyde for rats was determined to be 632 mg/kg, using the enolic sodium salt, sodium β-oxyacrolein. This value represents the most accurate estimation of the acute toxicity of free malonaldehyde. The LD 50 of malonaldehyde calculated from that of the ethoxy derivative, 1,1,3,3-tetraethoxypropane ...
D L, Crawford, R O, Sinnhuber, F M, Stout, J E, Oldfield, J, Kaufmes   +4 more
openaire   +2 more sources

Evaluation of the Acute Toxicity of Silahydrocarbon

AIHAJ, 1991
Silahydrocarbon (SHC) is a base stock for a candidate high-temperature hydraulic fluid. Because United States Air Force personnel working with SHC may be exposed to potential health hazards, a complete battery of acute toxicity tests was performed with the fluid.
E R, Kinkead, S K, Bunger, R E, Wolfe, C R, Doarn   +3 more
openaire   +2 more sources

Acute Toxic Nephrosis

Postgraduate Medicine, 1952
Acute toxic nephrosis is believed to be the best term applied to acute tubular disorders characterized by shock, acute renal insufficiency with anuria, oliguria, uremia and heart failure and their associated phenomena. Histologically there is degeneration or necrosis of the tubular epithelium which at times may be more physiologic than pathologic ...
openaire   +2 more sources

Acute fluoride toxicity

British Dental Journal, 1982
K W, Stephen, W J, Collins, D R, McCall, T K, Watkins   +3 more
  +9 more sources

Acute toxicity studies with oxamyl

Fundamental and Applied Toxicology, 1986
The acute toxicity of oxamyl, an insecticide and nematicide, has been evaluated to establish proper handling guides. The material is highly toxic when given as a single oral dose; its LD50 is in fasted rats 2.5 to 3.1 mg/kg, 2.3 to 3.3 mg/kg in fasted mice, and 7 mg/kg in guinea pigs. A beagle dog given 30 mg/kg died, while 15 mg/kg was not lethal.
openaire   +2 more sources

The acute toxicity of pesticides to rats

Toxicology and Applied Pharmacology, 1960
Abstract 1. 1. LD50 values for 42 pesticides and 2 metabolites of DDT administered in a single dose by the oral or dermal route to Sherman strain adult rats have been determined. 2. 2. A comparison of laboratory results and use experience indicates that there is a much closer relationship between dermal LD50 values and the occurrence of ...
openaire   +2 more sources

Acute Toxicity

Abstract Acute toxicity can be assessed based on data from appropriately conducted dose-escalation studies or short-duration dose-ranging studies. The principles of assessing acute and sub-acute toxicity are explained.
Phil Ambery, Adrian Kilcoyne, Daniel O’Connor   +2 more
  +4 more sources

Hepcidin in acute iron toxicity

The American Journal of Emergency Medicine, 2009
Hepcidin regulates extracellular iron concentration by inhibiting iron release from macrophages and preventing iron absorption in the intestine. Our objective was to evaluate the expression of hepcidin in the liver in acute iron poisoning in a rat model.Male Wistar rats were assigned to group 1, who received 750 mg/kg elemental iron (LD(50)) by gavage,
Michal, Toledano, Eran, Kozer, Lee H, Goldstein, Ibrahim, Abu-Kishk, Adina, Bar-Haim, Yariv, Siman-Tov, Moshe, Rechavi, Gideon, Rechavi, Orly, Weizer-Stern, Matitiahu, Berkovitch   +9 more
openaire   +2 more sources

The acute toxicity of 2-benzylaminopyridine

Toxicology and Applied Pharmacology, 1976
Abstract 2-Benzylaminopyridine (2-BAP) has been suspected of causing adverse reactions in man including headache, malaise, and skin rash. The purpose of this investigation was to determine and partially characterize the acute toxicity of 2-BAP. In mice the estimated LD50 of 2-BAP dissolved in equimolar HCl was 1187 mg/kg po and 224 mg/kg ip.
L C, Griffis, R B, Forney
openaire   +2 more sources

Radiation therapy‐associated toxicity: Etiology, management, and prevention

Ca-A Cancer Journal for Clinicians, 2021
Kyle Wang
exaly