Systematic review and network meta-analysis of the efficacy, safety and tolerability of xanomeline plus trospium chloride compared with eight oral antipsychotics for the acute treatment of schizophrenia [PDF]
Journal of Comparative Effectiveness ResearchAim: The recently approved first-in-class combination therapy xanomeline/trospium chloride (KarXT) demonstrated superiority over placebo in three randomized controlled trials (RCTs) of adults with schizophrenia.
Conor Hickey +11 more
doaj +2 more sources
IDENTIFICATION AND QUANTIFICATION OF VERAPAMIL IN BLOOD AND URINE [PDF]
Journal of IMAB, 2020 Purpose: To adapt and validate an HPLC method for verapamil determination in blood and urine samples. Materials/Methods: Identification of verapamil and its metabolites was made by means of gas-chromatography, using Agilent 7890B/5977A GC-MS system ...
Georgi Bonchev +3 more
doaj +1 more source
A UHPLC METHOD FOR SERTRALINE DETERMINATION [PDF]
Journal of IMAB, 2017 Purpose: To develop and implement a UHPLC method for quantitative determination of sertraline in biological samples – mostly human blood and urine. Material&Methods: Blood and urine samples available from Laboratory of analytical toxicology and Clinic ...
Georgi Bonchev +4 more
doaj +1 more source
AN OPTIMIZED GC-MS METHOD FOR AMPHETAMINES IDENTIFICATION [PDF]
Journal of IMAB, 2017 Purpose: To develop a reliable method for qualitative determination of amphetamines in biological samples, that combines simplicity, sensitiveness and robustness.
Georgi Bonchev +3 more
doaj +1 more source
ACUTE METHANOL INTOXICATIONS – A CHALLENGE FOR CLINICAL TOXICOLOGY [PDF]
Journal of IMAB, 2016 Purpose: Methanol (CH3OH) is a monohydric alcohol, vastly used both in housekeeping and industry. Although the acute methanol intoxications are rare, they may include life-threatening symptoms, substantial lethality and negative consequences such as ...
Petko Marinov +5 more
doaj +1 more source
„I ride with you“ – active promotion of mental health in Bulgaria
European Psychiatry, 2022 Introduction One of the main concepts of mental health promotion is proactivity, rather than reactivity. As psychiatrists we must be the first line of mental health advocacy and to do so we must share clear messages and take definitive actions ...
K. Guevara
doaj +1 more source
CIGUATERA POISONING: PACIFIC DISEASE, FOODBORNE POISONING FROM FISH IN WARM SEAS AND OCEANS. Review [PDF]
Journal of IMAB, 2017 Purpose: The review is provoked because of lack of awareness of the medical practitioners in Bulgaria concerning of the ethnology, pathogenesis, clinical symptoms and treatment of the ciguatera fish poisoning (CFP).
Snezha Zlateva +5 more
doaj +1 more source
ACUTE POISONING WITH BENZODIAZEPINES AND OTHER HYPNOTICS: ETIOLOGIC CAUSE, SEX/AGE DISTRIBUTION AND CLINICAL OUTCOME [PDF]
Journal of IMAB, 2016 Purpose: Poisoning with drugs occupies a leading position among the causes of acute intoxications. Etiological distribution of medicated poisoning in different countries, even if they are adjacent, is different.
Petko Marinov +6 more
doaj +1 more source
ACUTE NARCOTIC DRUG INTOXICATIONS: ETIOLOGY, SEX/AGE DISTRIBUTION AND CLINICAL OUTCOME [PDF]
Journal of IMAB, 2017 Purpose: Poisoning with drugs is a serious medical and social problem worldwide. Retrospective analysis of acute poisoning with narcotic drugs had been performed in Varna region for 25 years (1991-2015).
Petko Marinov +6 more
doaj +1 more source
Journal of IMAB, 2018 Purpose: To perform a retrospective analysis of mushroom poisonings in Varna region for 25 years (1991-2015). Mushroom poisonings account for 10.7% of hospitalizations associated with acute exogenous intoxication.
Petko Marinov +5 more
doaj +1 more source