Results 281 to 290 of about 154,675 (336)

Designing Enzymatic Reactivity with an Expanded Palette

ChemBioChem, EarlyView.
Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley   +1 more source

Purification and Biochemical Characterization of theMycobacterium tuberculosis β-Ketoacyl-acyl Carrier Protein Synthases KasA and KasB [PDF]

, 2001
Merrill L. Schaeffer, Gautam Agnihotri, Craig Volker, Howard Kallender, Patrick J. Brennan, John T. Lonsdale   +5 more
openalex   +1 more source

Challenges and achievements of peptide synthesis in aqueous and micellar media

ChemBioChem, Accepted Article.
Peptides are being increasingly explored for drug development as well as other applications, ranging from research tools to food additives. This growing interest in peptides has led to the need to develop new sustainable synthetic approaches for this class of molecules. The present review article focuses on the synthesis of peptides in aqueous media to
Alessandro Angelini, Alessandro Scarso, Francesca Bordignon   +2 more
wiley   +1 more source

Identification, Substrate Specificity, and Inhibition of theStreptococcus pneumoniae β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH) [PDF]

, 2001
Sanjay S. Khandekar, Daniel R. Gentry, Glenn S. Van Aller, Patrick V. Warren, Hong Xiang, Carol Silverman, Michael L. Doyle, Pamela A. Chambers, Alex K. Konstantinidis, Martín Brandt, R. A. DAINES, John T. Lonsdale   +11 more
openalex   +1 more source

Cold‐Adapted Lipid A from Polaribacter sp. SM1127: A Study of Structural Heterogeneity and Immunostimulatory Properties

ChemBioChem, EarlyView.
This analysis reveals structural heterogeneity in the lipopolysaccharide lipid A from the cold‐adapted Gram‐negative bacterium Polaribacter sp. SM1127, with variations in fatty acid chain number, length, branching, saturation, and hydroxylation degree, likely aiding bacterial adaptation to cold environmental stressors. Lipopolysaccharide is shown to be
Roberta Cirella, Emanuela Andretta, Luca De Simone Carone, Francesca Olmeo, Mei‐Ling Sun, Yu‐Zhong Zhang, Marcello Mercogliano, Antonio Molinaro, Alba Silipo, Flaviana Di Lorenzo   +9 more
wiley   +1 more source

Expression and purification of four different rhizobial acyl carrier proteins The GenBank accession numbers for the nucleotide sequences reported in this paper are AF159244 and AF159243 for the acpP-containing regions of Sinorhizobium meliloti 1021 and of Rhizobium leguminosarum LPR5045, respectively.

, 2000
Isabel M. López‐Lara, Otto Geiger
openalex   +1 more source

SAAP‐148 Oligomerizes into a Hexamer Forming a Hydrophobic Inner Core

ChemBioChem, EarlyView.
The highly cationic and hydrophobic antimicrobial peptide SAP‐148 effectively eradicates multidrug‐resistant bacteria, persistent cells, and biofilms without inducing resistance. Its efficiency is likely due to its ability to disrupt bacterial membranes as an oligomer, forming a stable alpha‐helical hexameric bundle with three parallel dimers that ...
Aden Hodzic, Djenana Vejzovic, Altea Topciu, Kirill Kuhlmann, Raj Kumar, Maria Andrea Mroginski, Alejandra de Miguel, Pia Hofmann, Klaus Zangger, Markus Weingarth, Robert A. Cordfunke, Jan W. Drijfhout, Peter Nibbering, Michal Belicka, Karl Lohner, Nermina Malanovic   +15 more
wiley   +1 more source

Rv0100, a proposed acyl carrier protein in Mycobacterium tuberculosis: expression, purification and crystallization. Corrigendum. [PDF]

Acta Crystallogr F Struct Biol Commun, 2020
Bondoc JMG, Gutka HJ, Almutairi MM, Patwell R, Rutter MW, Wolf NM, Samudrala R, Mehboob S, Dementiev A, Abad-Zapatero C, Movahedzadeh F.   +10 more
europepmc   +1 more source

Covalent Peptide‐Graphene Conjugates for Enhanced Cell Spreading, Osteogenic Differentiation, and Angiogenesis in Bone Defects

ChemBioChem, Accepted Article.
Traumatic bone injury is one of the most common injuries that require surgical intervention, and current treatments suffer severe drawbacks. Modern research in bone regeneration focuses on implants will support and enhance native tissue regeneration. One scaffold material that shows promise is graphene oxide (GO), a 2D nanomaterial made from oxidation ...
Michelle Elise Wolf, Yaxuan Liu, Jason D. Orlando, Jingzhi Zhou, Stefanie Arlene Sydlik   +4 more
wiley   +1 more source

Catalysis in Chemical Modification of Proteins

ChemCatChem, EarlyView.
Catalytic principles of synthetic organic chemistry have been increasingly applied to chemical modification of proteins during the recent years. This review article describes how seven types of catalytic systems —electrocatalysis, photocatalysis, metal catalysis, acid catalysis, organocatalysis, supramolecular catalysis, and heterogeneous catalysis ...
Seiya Ishizawa, Koki Fujimura, Kounosuke Oisaki, Shinichi Sato, Jun Ohata   +4 more
wiley   +1 more source