Results 281 to 290 of about 80,359 (315)
Colorimetric Assay Reports on Acyl Carrier Protein Interactions. [PDF]
Sci Rep, 2019 Acheampong KK +5 more
europepmc +1 more source
Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application
Exploration, EarlyView.This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang +4 more
wiley +1 more source
Food Biomacromolecules, EarlyView.Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo +3 more
wiley +1 more source
Characterization of Acyl Carrier Protein-Dependent Glycosyltransferase in Mitomycin C Biosynthesis. [PDF]
Biochemistry, 2019 Nguyen HP, Yokoyama K.
europepmc +1 more source
The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance
Glia, EarlyView.Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons during rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic lipids and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production of ...
Rose Follis +2 more
wiley +1 more source
Modifying the Thioester Linkage Affects the Structure of the Acyl Carrier Protein. [PDF]
Angew Chem Int Ed Engl, 2019 Sztain T +5 more
europepmc +1 more source
Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism
International Journal of Cancer, EarlyView.Abstract Abnormal epigenetic patterns are crucial for the progression of metabolic‐associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC) development. Recent research focused on the interplay between epigenetics and altered metabolic pathways in HCC from MASLD, suggesting that the reversibility of epigenetic changes offers ...
Chiara Aiello +7 more
wiley +1 more source
Microbiota humanization drives human‐like metabolic and immune transcriptomic shifts in pigs
iMetaOmics, EarlyView.This study successfully established gut microbiota‐humanized pigs, achieved human‐like remodeling of the serum metabolome, and uncovered transcriptional alterations in immune cell subsets. These findings advance our understanding of how human gastrointestinal microorganisms affect host metabolism and the immune function in a porcine model.
Zhaoqi Zhang +9 more
wiley +1 more source
iMeta, EarlyView.In this study, we found evidence of phage‐mediated horizontal transfer of virulence genes in Salmonella enterica in global habitats from a molecular evolutionary perspective. Notably, csrA, a global regulator in Salmonella enterica, curbed horizontal gene transfer by inhibiting the cyclization and release of prophage.
Tianjing She +9 more
wiley +1 more source