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Nucleophilic Acyl Substitution of Acyl Diimides

The Journal of Organic Chemistry, 2009
The nucleophilic acyl substitution of the acyl diimide intermediate formed by the oxidation of isoniazid was found to involve two methanol molecules in a six-membered cyclic transition state. Calculations were performed in the gas phase at the B3LYP/6-311+G(d,p)//B3LYP/6-31G(d) level of theory and solvation effects were included both explicitly and ...
Brian F. Yates   +3 more
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S-Acylation of Proteins [PDF]

open access: possible, 2019
Palmitoylation or S-acylation is the posttranslational attachment of fatty acids to cysteine residues and is common among integral and peripheral membrane proteins. Palmitoylated proteins have been found in every eukaryotic cell type examined (yeast, insect, and vertebrate cells), as well as in viruses grown in these cells.
Ludwig Krabben   +3 more
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Acylation of plant acyl carrier proteins by acyl-acyl carrier protein synthetase from Escherichia coli

Archives of Biochemistry and Biophysics, 1984
The acyl-acyl carrier protein synthetase from Escherichia coli has been examined for its ability to specifically acylate acyl carrier protein (ACP) from higher plants in order to develop an assay for plant ACP, and to prepare labeled acyl-ACP of plant origin. It was found that the E.
Tsung Min Kuo, John B. Ohlrogge
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Aromatic acyl phosphates as substrates of acyl phosphatase

Archives of Biochemistry and Biophysics, 1966
Two aromatic acyl phosphates, benzoyl phosphate and p-nitrobenzoyl phosphate, were synthesized and some of their properties were studied. Both are split by purified muscle acyl phosphatase: their suitable optical characteristics, particularly of benzoyl phosphate, make it possible to use them as advantageous substrates for the continuous measurement of
RAMPONI, GIAMPIETRO   +2 more
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Selective acylation of hydroxy steroids with acyl cyanides [PDF]

open access: possibleCollection of Czechoslovak Chemical Communications, 1979
A mild acylation method of steroid alcohols with acyl cyanides is described. The high sensitivity of benzoyl cyanide toward steric conditions in the neighbourhood of the hydroxyl group was made use of for the separation of epimeric hydroxy steroids.
Milan Souček   +3 more
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Acyl hydrazines as precursors to acyl radicals

Tetrahedron, 2002
Abstract The use of acyl hydrazines (hydrazides) as precursors for the stoichiometric generation of acyl radicals is explored. Two classes of substrates are examined: unsubstituted acyl hydrazines and acyl hydrazines substituted with a leaving group (2-nitrobenzenesulfonyl or ‘nosyl’).
Rebecca Braslau   +5 more
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Acylation of pyrrolyltricarbonylmanganese. Structure of the acylation product

Journal of Organometallic Chemistry, 1977
Abstract The acylation of pyrrolyltricarbonylmanganese (PTM) is studied. The reaction proceeds in an unusual manner; introduction of an acetyl group into the α-position of the PTM pyrrolyl ligand is accompanied by extensive rearrangement of bonds resulting in the formation of a binuclear complex (π-C 4 H 4 N)Mn(CO) 3 (CH 3 COC 4 H 3 N)Mn(CO) 3 (I ...
V. G. Andrianov   +4 more
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