Results 251 to 260 of about 32,557 (330)

Commentary on “Are Individuals With Type 2 Diabetes Metabolically Inflexible? A Systematic Review and Meta‐Analysis”

open access: yes
Endocrinology, Diabetes &Metabolism, Volume 8, Issue 4, July 2025.
Katerina Koudelkova   +2 more
wiley   +1 more source

Elucidation of Mechanism of Action in Drug Invention: Using Stable Isotope Tracers to Unravel Biochemical Kinetics

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT The invention of a therapeutic begins by characterizing features that differentiate healthy versus diseased states; this often presents as changes in the concentration of an analyte. Examples include elevated blood glucose in diabetes, high cholesterol in heart disease, and protein aggregation in neurodegeneration.
Rebecca A. Kohnz   +10 more
wiley   +1 more source

Genetic and transcriptomic analysis of lentil seed imbibition and dormancy in relation to its domestication

open access: yesThe Plant Genome, Volume 18, Issue 2, June 2025.
Abstract Seed dormancy is an adaptation that delays germination to prevent the start of this process during unsuitable conditions. It is crucial in wild species but its loss was selected during crop domestication to ensure a fast and uniform germination. Water uptake, or imbibition, is the first step of germination.
Azalea Guerra‐García   +5 more
wiley   +1 more source

Elucidation and reconstitution of hydrolyzable tannin biosynthesis. [PDF]

open access: yesPlant Biotechnol (Tokyo)
Tahara K, Milkowski C, Oda-Yamamizo C.
europepmc   +1 more source

A maize landrace introgression library reveals a negative effect of root‐to‐shoot ratio on water‐use efficiency

open access: yesThe Plant Genome, Volume 18, Issue 2, June 2025.
Abstract Novel sources of genetic variability for water‐use efficiency (WUE) are needed in order to breed varieties more suitable to sustainable cropping systems. Here, a maize (Zea mays L.) introgression library of the landrace Gaspé Flint into the reference line B73 was characterized in high‐throughput phenotyping platforms, both in well‐watered and ...
Giuseppe Sciara   +9 more
wiley   +1 more source

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