Results 271 to 280 of about 32,557 (330)

Ecotype‐specific phenolic acid accumulation and root softness in Salvia miltiorrhiza are driven by environmental and genetic factors

open access: yesPlant Biotechnology Journal, Volume 23, Issue 6, Page 2224-2241, June 2025.
Summary Salvia miltiorrhiza Bunge, a renowned medicinal herb in traditional Chinese medicine, displays distinctive root texture and high phenolic acid content, traits influenced by genetic and environmental factors. However, the underlying regulatory networks remain unclear.
Haomiao Yu   +13 more
wiley   +1 more source

Phospholipid Acyltransferases: Characterization and Involvement of the Enzymes in Metabolic and Cancer Diseases. [PDF]

open access: yesCancers (Basel)
Korbecki J   +8 more
europepmc   +1 more source

Rubber biosynthesis drives the biogenesis and development of rubber particles, the rubber‐producing organelles

open access: yesPlant Biotechnology Journal, Volume 23, Issue 6, Page 2303-2316, June 2025.
Summary Rubber particles (RPs) are specialized organelles for the biosynthesis and storage of natural rubber in rubber‐producing plants. However, the mechanisms underlying the biogenesis and development of RPs remain unclear. In this study, two latex‐specific cis‐prenyltransferases (CPTs), TkCPT1 and TkCPT2, were identified in Taraxacum kok‐saghyz ...
Tiancheng Xu   +15 more
wiley   +1 more source

Intragenic PNPLA1 duplication in Labrador retrievers with nonepidermolytic ichthyosis

open access: yesVeterinary Dermatology, Volume 36, Issue 3, Page 314-320, June 2025.
Background – Ichthyoses represent a heterogeneous group of cornification disorders characterised by epidermal scaling. Objectives – To describe the clinical, histopathological and genetic analysis of a Labrador retriever with nonepidermolytic ichthyosis, and the results of a Labrador retriever population screening for a newly detected PNPLA1 genomic ...
Stefan J. Rietmann   +7 more
wiley   +1 more source

First Steps toward the Design of Peptides that Influence the Intracellular Palmitoylation Machinery

open access: yesChemBioChem, Volume 26, Issue 10, May 27, 2025.
Herein, DC peptides consisting of the cell‐penetrating peptide sC18* and a Asp–His–His–Cys (DHHC) motif derived from human ZDHHC palmitoyltransferase are highlighted. DC peptides demonstrate high cellular internalization into various cellular models, exert cytotoxic effects against cancerous cells, and alter the function and localization of known ...
Katharina Stillger   +7 more
wiley   +1 more source

Reduced Palmitoylation of SQSTM1/p62 in Huntington Disease Is Associated With Impaired Autophagy

open access: yesThe FASEB Journal, Volume 39, Issue 9, 15 May 2025.
Sequestosome 1 (SQSTM1)/p62 is a receptor for autophagy required to deliver damaged organelles and aggregated proteins to the lysosome for degradation. SQSTM1 undergoes palmitoylation, the reversible addition of the saturated fatty acid palmitate to cysteines.
F. Abrar   +12 more
wiley   +1 more source

Inhibition of zDHHC7-driven protein S-palmitoylation prevents cognitive deficits in an experimental model of Alzheimer's disease. [PDF]

open access: yesProc Natl Acad Sci U S A
Natale F   +8 more
europepmc   +1 more source

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