Results 281 to 290 of about 24,285 (335)

Local adaptation of both plant and pathogen: an arms‐race compromise in switchgrass rust

New Phytologist, Volume 248, Issue 3, Page 1527-1541, November 2025.
Summary In coevolving species, parasites locally adapt to host populations as hosts locally adapt to resist parasites. Parasites often outpace host local adaptation since they have rapid life cycles, but host diversity, the strength of selection, and external environmental influence can result in complex outcomes.
Acer VanWallendael, Chathurika Wijewardana, Jason Bonnette, Lisa Vormwald, Felix B. Fritschi, Arvid Boe, Shelly Chambers, Robert B. Mitchell, Francis M. Rouquette Jr, Yanqi Wu, Philip A. Fay, Julie D. Jastrow, John T. Lovell, Thomas E. Juenger, David B. Lowry   +14 more
wiley   +1 more source

Treatment of a case with short stature and Goltz syndrome with long-acting growth hormone: a case report and follow-up. [PDF]

BMC Pediatr
Zhang J, Qiao N, Li X.
europepmc   +1 more source

KAT2A‐H3K79succ‐Mediated SH2B3 Upregulation Promotes TNBC Metastasis Through Diminishing the Ubiquitin‐Dependent Degradation of Vimentin

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Lysine acetyltransferase 2A (KAT2A) is a critical catalytic component within transcriptional regulatory complexes and plays a significant role in triple‐negative breast cancer (TNBC). To investigate its underlying mechanism, this study demonstrates that KAT2A catalyzes succinylation at the H3K79 site to promote SH2B3 transcription and enhance its ...
Xiaohui Shi, Ran Hao, Zhan Yang, Xiaoran Wang, Yiwei Lu, Xiaohan Wang, Huanqi Ji, Shen Ma, Xuehua Liu, Jie Hu, Yixin Qi   +10 more
wiley   +1 more source

Comparative Analysis of Age-Associated Changes in Meibum Composition, Distribution, and Function in Mice With Altered Hyaluronan Expression. [PDF]

Invest Ophthalmol Vis Sci
Verma S, Montoya PAG, Sun M, Puri S, Yuksel S, Wilkerson A, Gesteira TF, Butovich IA, Coulson-Thomas VJ.   +8 more
europepmc   +1 more source

Homeostatic Counter‐Regulation Mediates Spermidine‐Induced Triacylglyceride Reduction in Drosophila melanogaster—From Phenotype to Molecular Mechanism

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
In Drosophila melanogaster females fed a standard diet containing 2.5% yeast extract (low‐yeast diet), spermidine (Spd) administration does not enhance the endogenous Spd pool but increases the excretion of catabolic N1‐acetylspermidine (N1AcSpd) and reduces fat stores. This process requires the catabolic Akh/AkhR pathway.
Kai Lüersen, Celina Runke, Bernhard Blank‐Landeshammer, Julian Weghuber, Ronald P. Kühnlein, Thomas Roeder, Gerald Rimbach   +6 more
wiley   +1 more source

Mechanisms Involved in Cell Wall Remodeling in Etiolated Rice Shoots Grown Under Osmotic Stress. [PDF]

Life (Basel)
Wakabayashi K, Shibatsugu M, Hattori T, Soga K, Hoson T.   +4 more
europepmc   +1 more source

Abnormal β‐Hydroxybutyrylation Modification of ARG1 Drives Reprogramming of Arginine Metabolism to Promote the Progression of Colorectal Cancer

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Alterations in arginine metabolism and β‐hydroxybutyrylation (Kbhb) modifications play a critical role in tumor progression. This study reveals valuable insights into arginine metabolism reprogramming involving the ARG1‐Kbhb/P300/SLC3A2 signaling axis and uncovers an effective therapy combining BHB with ARG1 inhibitor through conventional enzymatic and
Chuman Lin, Zhiyang Li, Xiaotong Zhu, Wanbing Zhou, Xiansheng Lu, Jiali Zheng, Jie Lin   +6 more
wiley   +1 more source

On the origin of fatty acid biosynthesis in Archaeplastida. [PDF]

J Exp Bot
Kelly AA, Feussner I.
europepmc   +1 more source

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, Volume 45, Issue 10, Page 1247-1284, October 2025.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

Multi-Omics Mendelian Randomization Identifies a DNA Methylation-ZDHHC20-Immune Axis Associated With Schizophrenia Risk. [PDF]

Brain Behav
Guo Q, Chen C, Wang Y, Guo L, Shang S.
europepmc   +1 more source