Results 41 to 50 of about 2,332,279 (317)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

A simulation study on strength and fatigue analysis of hydraulic excavator buckets

Frontiers in Mechanical Engineering
The bucket of industrial hydraulic excavator is one of the key components in the excavator. Considering the poor model construction ability of the current bucket strength and fatigue simulation method of industrial hydraulic excavator, which leads to the
Wenbin Pan
doaj   +1 more source

Generalized fractional maximal and integral operators on Orlicz and generalized Orlicz--Morrey spaces of the third kind

, 2018
In the present paper, we will characterize the boundedness of the generalized fractional integral operators $I_{\rho}$ and the generalized fractional maximal operators $M_{\rho}$ on Orlicz spaces, respectively.
Deringoz, Fatih, Guliyev, Vagif S., Nakai, Eiichi, Sawano, Yoshihiro, Shi, Minglei   +4 more
core   +1 more source

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

The Lancet, 2021
Summary Background In this study, we aimed to evaluate the effects of tocilizumab in adult patients admitted to hospital with COVID-19 with both hypoxia and systemic inflammation.
O. Abani, A. Abbas, F. Abbas, M. Abbas, Sadia Abbasi, H. Abbass, A. Abbott, N. Abdallah, A. Abdelaziz, M. Abdelfattah, B. Abdelqader, B. Abdul, A. Abdul Rasheed, A. Abdulakeem, R. Abdul-Kadir, A. Abdulmumeen, R. Abdul-Raheem, N. Abdulshukkoor, K. Abdusamad, Y. Abed El Khaleq, M. Abedalla, A. Abeer Ul Amna, K. Abernethy, A. Aboaba, H. Abo-Leyah, A. Abou-Haggar, M. Abouibrahim, M. Abraham, T. Abraham, A. Abraheem, J. Abrams, Hyacinth-John Abu, A. Abu-Arafeh, S. M. Abubacker, A. Abung, Y. Aceampong, A. Achara, D. Acharya, S. Acheampong, J. Acheson, A. Acosta, C. Acton, J. Adabie-Ankrah, F. Adam, M. Adam, H. Adamali, C. Adams, C. Adams, K. Adams, R. Adams, T. Adams, K. Adcock, Jemaimah Addai, A. Adebiyi, K. Adegoke, V. Adell, Sherna F. Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, J. Adeyemi, R. Adhikary, G. Adkins, A. Adnan, J. Aeron-Thomas, D. Affleck, C. Afnan, M. Afridi, Z. Aftab, M. Agarwal, R. Agbeko, C. Agbo, P. Agent, S. Aggarwal, A. Aghababaie, S. Ahamed Sadiq, Mohamed H Ahammed Nazeer, Mohammad Ahmad, S. Ahmad, Asim A. Ahmed, B. Ahmed, F. Ahmed, H. Ahmed, Iram Ahmed, I. Ahmed, Khaled Ahmed, L. Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S Ahmed, Naseer Ahmed, N. Ahmed, O. Ahmed, R. Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Sara Ahmed, S. Ahmed, S. Ahmed, R. Ahmed Ali, Sana G Ahmed, S. Ahmer, D. Ail, M. Ainsworth, M. Aissa, L. Aitken, B. Ajay, A. Ajibode, A. Ajmi, N. Akhtar, N. Akhtar, S. Akili, O. Akindolie, Y. Akinfenwa, O. Akinkugbe, O. Aktinade, Ahmad Al Aaraj, A. Al Balushi, M. Al Dakhola, A. Al Swaifi, E. Al-Abadi, N. Aladangady, A. Alam, S. Alam, A. Al-Asadi, K. Alatzoglou, P. Albert, L. Albon, G. Alcorn, S. Alcorn, A. Aldana, D. Alderdice, R. Aldouri, J. Aldridge, N. Aldridge, A. Alegria, A. Alexander, J. Alexander, Peter D G Alexander, Charlotte Alford, J. Al-fori, L. Alghazawi, B. Al-Hakim, S. Al-Hity, Ali Ali, Asad Ali, Fawzia R Ali, J. Ali, Mariam Ali, Mohammad Ali, Nayab Ali, O. Ali, Sakina Ali, Syed Ali, A. Alina, F. Aliyuda, K. Alizaedeh, M. Al-Jibury, S. Al-Juboori, M. Al-Khalil, M. Alkhusheh, F. Allan, A. Allanson, R. Allcock, E. Allen, K. Allen, L. Allen, P. Allen, R. Allen, S. Allen, Sharon A. Allen, S. Allen, K. Allison, B. Allman, L. Allsop, H. Al-Moasseb, M. Al-Obaidi, L. Alomari, A. Al-Rabahi, B. Al-Ramadhani, Z. Al-Saadi, I. Alshaer, R. Al‐Shahi Salman, W. Al-Shamkhani, B. Al-Sheklly, S. Altaf, M. Alvarez, M. Alzetani, S. Amamou, N. Amar, S. Ambalavanan, Sarah-Jayne Ambler, R. Ambrogetti, Chris Ambrose, A. Ameen, K. Amenyah, M. Amezaga, A. Amin, Amina Amin, K. Amin, S. Amin, T. Amin, A. Amjad, N. Amjad, V. Amosun, K. Amsha, P. Amy, A. Anand, S. Anandappa, Julie Anderson, L. Anderson, Michelle Anderson, N. Anderson, R. Anderson, Rory Anderson, Wendy Anderson, P. Andreou, A. Andrews, Antonette Andrews, Jill Andrews, K. Aneke, A. Ang, W. W. Ang, T. Angel, A. Angela, P. Angelini, L. Anguvaa, O. Anichtchik, M. Anim-Somuah, K. Aniruddhan, Marie Anne Ledingham, J. Annett, Patrick J Anstey, R. Anstey, A. Anthony, A. Anthony-Pillai, P. Antill, Z. Antonina, V. Anu, M. Anwar, A. Apostolopoulos, D. Appleyard, M. Aquino, B. Araba, S. Aransiola, M. Araujo, A. Archer, D. Archer, S. Archer, C. Ardley, A. Arias, R. Arimoto, C. Arkley, C. Armah, I. Armata, A. Armitage, C. Armstrong, M. Armstrong, S. Armstrong, P. Armtrong, H. Arndt, C. Arnison-Newgass, D. Arnold, R. Arnold, D. Arora, K. Arora, P. Arora, R. Arora, A. Arter, A. Arya, R. Arya, D. Asandei, A. Asghar, C. Ashbrook-Raby, H. Ashby, J. Ashcroft, J. Ashcroft, S. Ashcroft, D. Asher, Ayesha Binte Ashfaq, A. Ashish, S. Ashman-Flavell, S. Ashok, A. Ashour, M. Ashraf, Saima Ashraf, Mohammad B Ashraq, D. Ashton, S. Ashton, A. Ashworth, R. Ashworth, A. Aslam, H. Asogan, A. Asrar, Omar Assaf, R. Astin-Chamberlain, D. Athorne, B. Atkins, C. Atkins, S. Atkins, J. Atkinson, V. Atkinson, B. Atraskiewicz, A. A. Attia, Rita Atugonza, P. Aubrey, A. Aujayeb, A. C. L. Aung, H. Aung, K. T. Aung, Y. Aung, Z. Aung, E. Austin, K. Austin, A. Auwal, M. Avery, J. Avis, G. Aviss, C. Avram, P. Avram, G. Awadzi, A. Awan, A. Aya, E. Ayaz, A. Ayers, J. Azam, M. Azharuddin, Ghazala Aziz, N. Aziz, A. Azkoul, A. Azman Shah, G. Azzopardi, H. Azzoug, F. Babatunde, Melvin Babi, B. Babiker, G. Babington, M. Babirecki, M. Babores, Adetona O Babs-Osibodu, S. Bacciarelli, R. Bachar, G. Bacon, J. Bacon, B. Badal, Gurpreet R Badhan, S. Badhrinarayanan, Joseph P Bae, Sibel Bafekr, A. Baggaley, A. Baggott, G. Bagley, D. Bagmane, L. Bagshaw, K. Bahadori, J. Bailey, K. Bailey, Lindsey K. Bailey, Liz Bailey, Morgan Bailey, Pippa K. Bailey, S. Bailey, H. Baillie, J. Baillie, J. Bain, V. Bains, D. Baird, S. Baird, T. Baird, Y. Baird, A. Bajandouh, Evelyn Baker, J. Baker, J. Baker, K. Baker, Rebecca Baker, T. Baker, V. Baker, H. Bakere, N. Bakerly, M. Baker-Moffatt, N. Bakhtiar, P. Bakoulas, Niranjan Balachandran, A. Balan, T. Balaskas, M. Balasubramaniam, A. Balcombe, A. Baldwin, A. Baldwin, C. Baldwin, D. Baldwin, R. Baldwin-Jones, J. Balfour, Ceri Ball, K. Ballard, I. Balluz, C. Balmforth, E. Balogh, A. Baluwala, G. Bambridge, A. Bamford, A. Bamford, P. Bamford, A. Bamgboye, E. Bancroft, H. Bancroft, T. Bancroft, J. Banda, K. Bandaru, S. Bandi, N. Bandla, S. Bandyopadhyam, A. Banerjee, R. Banerjee, H. Banks, Luke Banks, P. Banks, O. Bannister, L. Banton, M. Baptist, T. Baqai, A. M. Baral, D. Baramova, R. Barber, E. Barbon, M. Barbosa, J. Barbour, A. Barclay, C. Barclay, G. Bardsley, S. Bareford, S. Bari, A. Barker, D. Barker, H. Barker, Joseph Barker, L. Barker, Oliver Barker, K. Barker-Williams, S. Barkha, J. Barla, G. Barlow, R. Barlow, V. Barlow, J. Barnacle, Alex Barnard, D. Barnes, N. Barnes, T. Barnes, C. Barnetson, A. Barnett, M. Barnett, A. Barnett-Vanes, W. Barnsley, A. Barr, D. Barr, S. Barratt, M. Barrera, A. Barrett, F. Barrett, J. Barrett, J. Bartholomew, C. Bartlett, G. Bartlett, G. Barton, J. Barton, L. Barton, R. Barton, R. Baruah, S. Baryschpolec, A. Bashyal, B. Basker, A. Basoglu, J. Bassett, G. Bassett, C. Bassford, B. Bassoy, V. Bastion, A. Basumatary, T. Bate, Harry J Bateman, K. Bateman, V. Bateman, E. Bates, H. Bates, Michelle Bates, Simon Bates, S. Batham, A. Batista, A. Batla, D. Batra, H. Batty, T. Batty, M. Baum, C. Bautista, F. Bawa, Fatima S Bawani, S. Bax, M. Baxter   +499 more
semanticscholar   +1 more source

Associations of Sleep and Shift Work with Osteoarthritis Risk

Arthritis Care &Research, Accepted Article.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships between circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000‐person cohort, we evaluated associations between sleep duration, sleeplessness/insomnia, and ...
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Biofumigation for the Management of Fusarium graminearum in a Wheat-Maize Rotation

Pathogens, 2022
Fusarium graminearum is the most important causal agent of head blight in wheat, and stalk and ear rot in maize. A field experiment was conducted to investigate the effect of incorporation of Brassicaceae cover crops on Fusarium graminearum in a wheat ...
Samina Ashiq, Simon Edwards, Andrew Watson, Matthew Back   +3 more
doaj   +1 more source

Differential Item Functioning on the Patient Health Questionnaire‐8 by Disease Subtype, Language, Sex, and Age among People with Systemic Sclerosis: A Scleroderma Patient‐centered Intervention Network Cohort Study

Arthritis Care &Research, Accepted Article.
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu, Marie‐Eve Carrier, Marie‐Claude Geoffroy, Meira Golberg, Linda Kwakkenbos, Susan J. Bartlett, Catherine Fortuné, Amy Gietzen, Karen Gottesman, Geneviève Guillot, Laura K. Hummers, Amanda Lawrie‐Jones, Vanessa L. Malcarne, Michelle Richard, Maureen Sauvé, Luc Mouthon, Andrea Benedetti, Brett D. Thombs, The SPIN Investigators, Claire E. Adams, Marie Hudson, Maureen D. Mayes, James Stempel, Robyn K. Wojeck, Christian Agard, Laurent Alric, Marc André, Floryan Beaslay, Elana J. Bernstein, Sabine Berthier, Lyne Bissonnette, Sophie Blaise, Eva Bories, Alessandra Bruns, Carlotta Cacciatore, Patricia Carreira, Marion Casadevall, Benjamin Chaigne, Lorinda Chung, Benjamin Crichi, Thylbert Deltombe, Christopher P. Denton, Tannvir Desroche, Robyn Domsic, James V. Dunne, Bertrand Dunogue, Regina Fare, Dominique Farge‐Bancel, Paul R. Fortin, Loraine Gauzère, Anne Gerber, Jessica K. Gordon, Brigitte Granel‐Rey, Aurélien Guffroy, Geneviève Gyger, Eric Hachulla, Daphna Harel, Monique Hinchcliff, Sabrina Hoa, Michael Hugues, Alena Ikic, Sindhu R. Johnson, Nader Khalidi, Kimberly S. Lakin, Marc Lambert, Maggie Larche, David Launay, Yvonne C. Lee, Paul Legendre, Catarina Leite, Hélène Maillard, Nancy Maltez, Joanne Manning, Isabelle Marie, Maria Martin Lopez, Thierry Martin, Ariel Masetto, Arsène Mekinian, Sheila Melchor Díaz, Morgane Mourguet, Christelle Nguyen, Karen Nielsen, Mandana Nikpour, Louis Olagne, Vincent Poindron, Janet Pope, Susanna Proudman, Grégory Pugnet, Loïc Raffray, François Rannou, Alexis Régent, Frederic Renou, Sébastien Rivière, David Robinson, Esther Rodríguez Almazar, Tatiana Sofia Rodríguez‐Reyna, Sophie Roux, Perrine Smets, Vincent Sobanski, Robert F. Spiera, Virginia Steen, Evelyn Sutton, Carter Thorne, Damien Vagner, John Varga, Pearce Wilcox, Vanessa Cook, Cassidy Dal Santo, Monica D'Onofrio, Elsa‐Lynn Nassar   +109 more
wiley   +1 more source

What specific plant traits support ecosystem services such as pollination, bio-control and water quality protection in temperate climates? A systematic map

Environmental Evidence, 2018
Background Agricultural intensification has contributed to increased diffuse source pollution within water catchments, reduced heterogeneity within the landscape and caused major declines in farmland wildlife. This decrease in biodiversity has been shown
Claire J. Cresswell, Heidi M. Cunningham, Andrew Wilcox, Nicola P. Randall   +3 more
doaj   +1 more source

Pan-cancer analysis of ADAMs: A promising biomarker for prognosis and response to chemotherapy and immunotherapy

Frontiers in Genetics, 2023
Background: Members of a disintegrin and metalloproteinase (ADAM) family play a vital role in cancer development. However, a comprehensive analysis of the landscape of the ADAM family in pan-cancer remains to be performed.Methods: The correlation of the ...
Bo Ma, Riyue Yu
doaj   +1 more source