Results 81 to 90 of about 13,148 (179)

Severe ADAMTS-13 deficiency without hemolysis as a cause of cryptogenic stroke: A single center case series

open access: yesJournal of Stroke and Cerebrovascular Diseases
Introduction: Cerebral Infarction due to Severe ADAMTS-13 Deficiency (CISAD) remains an underrecognized cause of cryptogenic stroke. Despite the absence of classic hematologic features, CISAD confers a risk of recurrent ischemic events if not promptly ...
Johanna Seiden, MD, MPH   +8 more
doaj   +1 more source

Редкое клиническое наблюдение тромботической тромбоцитопенической пурпуры у больной 16 лет [PDF]

open access: yes, 2016
Описание случая диагностики и течения тромботической тромбоцитопенической пурпуры у девочки 16 ...
Бадосова, Т. В.   +2 more
core   +1 more source

Advantages of horizontal centrifugation of platelet‐rich fibrin in regenerative medicine and dentistry

open access: yesPeriodontology 2000, EarlyView.
Abstract The aim of this comprehensive review was to evaluate comparative studies on horizontal and fixed‐angle centrifugation methods for preparing platelet‐rich fibrin (PRF). Furthermore, additional studies utilizing horizontal PRF (H‐PRF) were systematically investigated.
Nima Farshidfar   +6 more
wiley   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone   +1 more
wiley   +1 more source

血浆ADAMTS-13活性和NLR在急性肺血栓栓塞症中的诊断价值

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2021
目的探究急性肺血栓栓塞症(PTE)患者血浆血管性血友病因子(vWF)活性、血管性血友病因子裂解酶(ADAMTS-13)活性、中性粒细胞计数与淋巴细胞计数比率(NLR)健康对照组的表达差异,探究ADAMTS-13活性、NLR对于PTE患者的诊断意义。方法共纳入急性PTE患者64例及健康对照者30例,收集相关临床数据并采用酶联免疫吸附试验(ELISA)检测血浆ADAMTS-13活性、vWF活性,分析比较ADAMTS-13活性、vWF活性的组间差异及其与其他临床指标的相关性,绘制受试者工作特征曲线(ROC ...
胡子旋, 何婉媚, 曾勉
doaj  

Genome Sequencing in 19 Families With Bladder Exstrophy and Epispadias Complex Indicates Involvement of the ADGR ‐Gene Family

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1286-1305, June 2026.
ABSTRACT Bladder exstrophy and epispadias complex (BEEC) is one of the most severe congenital malformations of the urogenital tract, significantly impacting continence, sexual function, and renal function. To date, the only recurrent genetic aberration identified is the 22q.11.2 microduplication, but several candidate regions and genes including ...
Agneta Nordenskjöld   +9 more
wiley   +1 more source

Integrative genomic and functional characterization of ADAMTS3 reveals its inflammatory regulation via NF‐κB and STAT3 pathways in osteosarcoma

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Abstract Osteosarcoma (OS) is an aggressive bone malignancy characterized by genomic instability and extensive extracellular matrix (ECM) remodeling. Members of the ADAMTS family are matrix‐associated proteases implicated in tumorigenesis; however, their roles in OS remain poorly defined. This study provides a comprehensive genomic, transcriptomic, and
Ehed Muhammed Aymaz   +4 more
wiley   +1 more source

Stati ipercoagulativi nella malattia cardiovascolare [PDF]

open access: yes, 2013
La cardiopatia coronarica o ischemica è caratterizzata dalla modificazione della struttura e della funzione dell’ endotelio, nonché delle cellule muscolari lisce. Questo porta alla formazione di depositi di sostanza adiposa di colore giallastro(la placca
FREDIANELLI, BARBARA
core  

Secretome and Pathway Analysis of Stress Induced Disc Degeneration In Vitro

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Integrated secretome and phosphoprotein profiling of human nucleus pulposus cells revealed that IL‐1β and TLR2/6 activation induce a shared degenerative program, defined by consistent upregulation of IL‐6, IL‐8, GRO‐α, ICAM‐1, and MMP‐7 and convergence on NF‐κB/AP‐1 signaling.
Exarchos Kanelis   +4 more
wiley   +1 more source

A Network‐Based Approach to Understanding Key Signaling Pathways in Intervertebral Disc Biology

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
A literature‐based signaling network capturing the most relevant pathways in human nucleus pulposus cells was first constructed from curated biological evidence. The network was then translated into a system of ordinary differential equations to derive steady‐state solutions and define median baseline activity levels.
Sofia Tseranidou   +11 more
wiley   +1 more source

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