Results 81 to 90 of about 447 (133)

Daratumumab for relapsed refractory immune thrombotic thrombocytopenic purpura: initial response and long-term follow-up

Research and Practice in Thrombosis and Haemostasis
Background: Management of patients with refractory or frequently relapsing (r/r) immune thrombotic thrombocytopenic purpura (iTTP) remains challenging, with no established consensus on optimal therapeutic strategies.
Roman Schimmer, Jana van den Berg, Marissa Schraner, Alice Trinchero, Andreas Holbro, Johanna A. Kremer Hovinga, Jan-Dirk Studt   +6 more
doaj   +1 more source

Prophylactic use of recombinant ADAMTS-13 during pregnancy for congenital thrombotic thrombocytopenic purpura

Research and Practice in Thrombosis and Haemostasis
Background: Congenital thrombotic thrombocytopenic purpura (cTTP) related to ADAMTS-13 deficiency is associated with a maternal risk of death of 10% and a risk of fetal loss greater than 50% without treatment.
Éloïse Colliou, Agnès Ribes, Clotilde Gaible, Mathilde Marlas, David Ribes, Isabelle Labadens, Paul Guerby, Stanislas Faguer   +7 more
doaj   +1 more source

ADAMTS-13 gene expression in antiphospholipid syndrome Antifosfolipid sendromunda adamts-13 gen ekspresyonu

, 2011
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by recurrent thrombosis and fetal mortality. Thrombotic microangiopathy (TMA) is an important histological finding in catastrophic APS (CAPS) and in APS patients with nephropathy. Analysis of familial thrombotic throm-bocytopenic purpura patients showed that there are mutations in ...
TOPAL SARIKAYA, AYŞEGÜL, Hançer, Veysel Sabri, Küçükkaya, Reyhan Diz   +2 more
openaire   +1 more source

A CASE OF THROMBOTIC THROMBOCYTOPENIC PURPURA RELATED TO MALIGNITY AND CHEMOTHERAPY

Hematology, Transfusion and Cell Therapy
Objective: Thrombotic thrombocytopenic purpura (TTP) is a life-threatening multisystem disease. TTP progresses with Microangiopathic hemolytic anemia (MAHA), fever, thrombocytopenia, neurological symptoms, and renal failure.
Ebru Kavak Yavuz, Songül Beskisiz Dönen, Etem Özkaya, Esra Pirinççi, Abdullah Karakuş, Orhan Ayyıldız   +5 more
doaj   +1 more source

Serum biomarkers reflecting progression of knee osteoarthritis: a stage-based evaluation of TGF-β3, ADAMTS-4, ADAMTS-5, and MMP-13

BMC Musculoskeletal Disorders
Background Knee osteoarthritis (KOA) is a progressive degenerative joint disease characterized by extracellular matrix (ECM) degradation and dysregulated inflammatory signaling.
Omer Esmez, Zubeyde Ercan, Secil Yılmaz, Meryem Sedef Doğru   +3 more
doaj   +1 more source

Recombinant ADAMTS 13 in thrombotic thrombocytopenic pupura

Oncoscience, 2017
Scully, Marie, Hibbard, Christopher, Ewenstein, Bruce   +2 more
openaire   +2 more sources

PO20 | DYSFUNCTION OF THE ADAMTS-13 / VON WILLEBRAND FACTOR AXIS, MEDIATED BY NETOSIS, AS A DRIVER OF PROTHROMBOTIC STATE AND UNFAVORABLE PROGNOSIS IN ONCOGYNECOLOGICAL PATIENTS

Bleeding, Thrombosis and Vascular Biology
Introduction. An imbalance between von Willebrand factor (VWF) and its primary protease, ADAMTS-13, plays a crucial role in the pathogenesis of microthrombosis and endotheliopathy.
Alexander Makatsariya
doaj  

A chronic recurrent course of moschcowitz disease

Терапевтический архив, 2008
I I Kalinina, O V Stalina, V V Ryzhko, N V Tsvetaeva, S A Vasil'ev, V I Petrova   +5 more
doaj  

Is ADAMTS-13 deficiency specific for thrombotic thrombocytopenic purpura? No [PDF]

Journal of Thrombosis and Haemostasis, 2003
openaire   +2 more sources

Thrombotic microangiopathies: role of ADAMTS-13.

JPMA. The Journal of the Pakistan Medical Association, 2012
Salman Naseem, Adil, Farheen, Karim
openaire   +1 more source