Results 231 to 240 of about 1,206,348 (301)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

When South Meets North: A Joint Contact Zone Coinciding With Environmental Gradients in Three Boreal Tree Species. [PDF]

Mol Ecol
Herrera-Egoavil P, Leal JL, Zhou Q, Milesi P, Lascoux M, Yıldırım B.   +5 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Environmental Gradients Decouple Demographic and Adaptive Connectivity in a Highly Mobile Coastal Marine Species. [PDF]

Mol Ecol
Brauer CJ, Bertram A, Sandoval-Castillo J, Fowler A, Bell JD, Hamer P, Wellenreuther M, Beheregaray LB.   +7 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Transcriptional adaptation of rumen papillae to high-grain diet reveals distinct temporal phases and SARA susceptibility signatures. [PDF]

J Anim Sci Biotechnol
Duszka K, Castillo-Lopez E, Hartinger T, Redmer T, Wagner N, Biber P, Atif RM, Aigensberger M, Schwartz-Zimmermann H, Kvalem Soto E, Dengler F, Berthiller F, Reisinger N, Zebeli Q, Kreuzer-Redmer S.   +14 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Novel Perspective of Hormesis in Evolution. [PDF]

Biology (Basel)
Vargas-Hernandez M, Munguia-Fragozo PV, Rivero-Montejo SJ, Amaya-Cruz DM, Vera-Morales JM, Ocampo-Velazquez RV, Macias-Bobadilla I, Torres-Pacheco I.   +7 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Uncovering shared and tissue-specific molecular adaptations to intermittent fasting in liver, brain, and muscle. [PDF]

Elife
Fan Y, De Silva S, Tabassum NI, Peng X, Lim VJT, Cheng X, Datta KK, Lowe R, Johns TG, Mattson MP, Mathivanan S, Sobey CG, Okun E, Liu YU, Chen G, Lai MKP, Jo DG, Gunaratne J, Arumugam TV.   +18 more
europepmc   +1 more source