Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco +18 more
wiley +1 more source
A `bright zone' in male hoverfly (Eristalis tenax) eyes and associated faster motion detection and increased contrast sensitivity [PDF]
Eyes of the hoverfly Eristalis tenax are sexually dimorphic such that males have a fronto-dorsal region of large facets. In contrast to other large flies in which large facets are associated with a decreased interommatidial angle to form a dorsal `acute ...
O'Carroll, David C. +2 more
core +2 more sources
Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster +11 more
wiley +1 more source
Custom Ocular Prosthesis for Enucleated Eye: A Case Report
The unfortunate loss or absence of an eye may be caused by a congenital defect, irreparable trauma, tumor, sympathetic ophthalmia, or the need for histologic confirmation of a suspected diagnosis.
Surya Narayan Pun +5 more
doaj +1 more source
Introduction The mismatch between training and testing data distribution causes significant degradation in the deep learning model performance in multi-ethnic scenarios.
Rishabh Jain +5 more
doaj +1 more source
Quantitative Assessment of Upper Limb Ataxia Using a Virtual Reality‐Based Evaluation System
ABSTRACT Objective Cerebellar ataxia impairs coordination and balance, reducing quality of life. Conventional clinical scales, including the Scale for the Assessment and Rating of Ataxia (SARA) and the International Cooperative Ataxia Rating Scale (ICARS), are widely used to assess ataxia but are limited by subjectivity and inter‐rater variability ...
Masayuki Sato +5 more
wiley +1 more source
Motion Aftereffects Due to Interocular Summation of Adaptation to Linear Motion [PDF]
The motion aftereffect (MAE) can be elicited by adapting observers to global motion before they view a display containing no global motion. Experiments y others have shown that if the left eye of an observer is adapted to motion going in one direction ...
Gruenwald, Alexander, Mingolla, Ennio
core +1 more source
Objective assessment of region of interest-aware adaptive multimedia streaming quality [PDF]
Adaptive multimedia streaming relies on controlled adjustment of content bitrate and consequent video quality variation in order to meet the bandwidth constraints of the communication link used for content delivery to the end-user.
Bogdan Ciubotaru +5 more
core +2 more sources
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Visual recovery from optic atrophy following acute optic neuropathy in the fellow eye
The left eye of a 65-year-old male was blind due to optic atrophy and only seeing eye had also dry type age-related macular degeneration. An anterior ischemic optic neuropathy developed in the better seeing eye.
Kemal Örnek, Nurgül Örnek
doaj

