Results 61 to 70 of about 539,031 (305)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Saccade Dynamics in the Acute and Recovery Phase of Abducens Nerve Palsy

Journal of Ophthalmic & Vision Research
Purpose: To examine the natural adaptive course of ocular motor system in unilateral abducens nerve palsy while addressing the scarce literature on saccade dynamics and natural adaptation.
Elissavet Kemanetzoglou, Klio Chatzistefanou, Nikolaos Smyrnis, Evangelia Kararizou, Evangelos Anagnostou   +4 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Dark-adapted red flash ERGs in healthy adults [PDF]

, 2018
Purpose: The x-wave of the dark-adapted (DA) ERG to a red flash reflects DA cone function. This exploratory study of healthy adults aimed to investigate changes in the DA red ERG with flash strength and during dark adaptation to optimise visualisation ...
A Chia, A Vincent, DL McCulloch, E Auerbach, ED Adrian, ED Adrian, G Schubert Von, GL Horowitz, H Kawabata, J François, JC Armington, JV Lovasik, JYC Cheng, K Motokawa, K. Graham, KM Nishiguchi, LY Chen, PI Sergouniotis, R Hamilton, R. Hamilton, RA Armstrong, S Mizunoya, S-H Lim, VA McBain, X Liu, Y Miyake   +25 more
core   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Transferable Modulation of Cognitive Control: The Cross-Task Role of Conflict Adaptation in Thematic Roles Assignment in Chinese

Behavioral Sciences
Conflict adaptation reflects the dynamic modulation of information processing by the cognitive control system following conflict detection. A central question in language processing research concerns whether control elicited by non-linguistic tasks ...
Jiefei Luo, Qi Cheng, Mengfang Zhang, Yan Wu   +3 more
doaj   +1 more source

Seeing the invisible: The scope and limits of unconscious processing in binocular rivalry [PDF]

, 2008
When an image is presented to one eye and a very different image is presented to the corresponding location of the other eye, they compete for conscious representation, such that only one image is visible at a time while the other is suppressed.
Sheng He, Zhicheng Lin
core   +1 more source

All eyes on rapid adaptive evolution [PDF]

Nature Reviews Genetics, 2018
A new study reveals that DNA methylation-mediated repression of gene expression regulates early eye development in blind cave morphs of Astyanax mexicanus.
openaire   +2 more sources

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Custom Ocular Prosthesis for Enucleated Eye: A Case Report

Journal of College of Medical Sciences-Nepal, 2016
The unfortunate loss or absence of an eye may be caused by a congenital defect, irreparable trauma, tumor, sympathetic ophthalmia, or the need for histologic confirmation of a suspected diagnosis.
Surya Narayan Pun, Rojina Shakya, Galav Adhikari, Prakash Kumar Parajuli, Raj Kumar Singh, Pramita Suwal   +5 more
doaj   +1 more source