Results 121 to 130 of about 1,695,526 (286)

Measuring strategy adaptivity [PDF]

open access: yes, 2018
Adapting ones strategy involves two steps: assessing and then modifying a strategy in a problem-solving environmentbased on performance. Schunn and Reder demonstrated a positive correlation between working memory and strategyadaptivity measured with the Air Traffic Control Task, though Schunn, Lovett, and Reder found no relationship betweenworking ...
Barnes, Kevin   +3 more
openaire  

Global Climate Change and the Funding of Adaptation [PDF]

open access: yes
Mitigation and adaptation are the most important strategies in combating global climate change. It is expected that in a post Kyoto world industrialized countries have to engage in greenhouse gas abatement, and to support developing countries in adapting
Gunter Stephan, Seraina Buob
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Adaptation, Mitigation and Innovation: A Comprehensive Approach to Climate Policy [PDF]

open access: yes
The ultimate question that most interests policy makers is how to reduce the climate change vulnerability of socio-economic systems in the most cost-effective manner. Extended literature has investigated the different dimensions of mitigation strategies,
Carlo Carraro   +3 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Ploidy’s Role in Daylily Plant Resilience to Drought Stress Challenges

open access: yesBiology
This study aimed to understand the differences in the performance of diploid and tetraploid daylily cultivars under water deficit conditions, which are essential indicators of drought tolerance.
Edvinas Misiukevičius   +2 more
doaj   +1 more source

Climate adaptation strategies

open access: yesA+BE: Architecture and the Built Environment, 2016
The previous chapter is an almost theoretical approach to study thermal comfort effects. The increasing complexity from an open field to a single building and finally a combination of various vegetation types gives insight in the relative effects of changes in the urban environment on thermal comfort.
openaire   +1 more source

Climate change: Pro-poor adaptation, risk management, and mitigation strategies [PDF]

open access: yes
Poverty reduction, Hunger, Climate change, Pro-poor strategies, Development planning, Adaptation measures, Policies, Land use and agriculture, Risk management,
Burton, Ian   +3 more
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy