Results 121 to 130 of about 5,788,215 (257)
SocietiesCrises such as pandemics, displacement, climate change, and economic downturns disrupt grassroots sport, undermining participation, equity, and resilience.
Simone Ciaccioni +6 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
, 2019 Introduction: Climate change has emerged as a major threat to Bangladesh. Higher and fluctuating temperatures and changes in rainfall caused by climate change and extreme weather events have reduced crop production.
Gow, Jeff +2 more
core +1 more source
Geodetski VestnikClimate change presents an increasing threat to agricultural, with significant impacts in viticulture. Rising temperatures affect grape yield, grape composition, and wine quality.
Igor Sirnik
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Climate change adaptation and the rental sector [PDF]
, 2013 The research employed an asset-based approach to understanding the capacities, assets and skills which tenants, landlords and housing managers bring to climate change adaptation. The project also took a pro-poor approach focusing on the adaptive capacity
Lesley Instone
core
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
An Analysis of Adaptation as a Response to Climate Change [PDF]
Climate change is likely to have relevant effects on our future socio-economic systems. It is therefore important to identify how markets and policy jointly react to expected climate change to protect our societies and well-being.
Francesco Bosello +2 more
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Extreme heat and climate change: adaptation in culturally and linguistically diverse (CALD) communities [PDF]
, 2013 Background: Several overseas studies have identified that people in ethnic minority groups are at greater risk during heatwaves. However, there is a paucity of information on this issue in Australia.
Peng Bi, Alana Hansen, Arthur Saniotis
core