Results 181 to 190 of about 7,062,162 (309)

Academic stress profiles and bedtime procrastination among college students: the mediating role of rumination and the moderating effect of perceived stress. [PDF]

Front Psychol
Xiang B, Li G, Xiang W.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Host immune responses and immune evasion mechanisms in Trypanosoma cruzi: implications for the immunopathogenesis of Chagas disease. [PDF]

Rev Soc Bras Med Trop
Andrade CMP.
europepmc   +1 more source

Transmit SENSE

Magnetic Resonance in Medicine, 2003
U. Katscher, P. Börnert, C. Leussler, J. S. van den Brink   +3 more
semanticscholar   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Passive subambient cooling and atmospheric water nexus. [PDF]

Nat Commun
Fang S, Dang S, Yang K, Zhou L, Ahmad S, Zhang Y, Li Q, Li Q, Chen W, Hazazi K, Qasem H, Wang J, Cao Y, Wu P, Saiari H, Gereige I, Gan Q.   +16 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Digital Inequality and Internet Self-Efficacy in Adults With Intellectual Disability: Motivational, Demographic and Contextual Predictors of Online Participation. [PDF]

J Appl Res Intellect Disabil
Glencross S, Mason J.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Case Report: The "delta effect": when endocrine pathology hides in plain sight. [PDF]

Front Endocrinol (Lausanne)
Voets PJGM.
europepmc   +1 more source