Results 51 to 60 of about 648,356 (307)
The ability of adaptive reasoning is a competence that must be possessed by students, but the reality of the field shows that students' adaptive reasoning ability is still not satisfactory.
Rizki Wahyu Yunian Putra
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
This research illustrates the construction of a computer-based multilevel adaptive test (MST) to estimate mathematics skills of students in Grade 10. The research shows that the test overcomes some of the limitations of linear and classical adaptive ...
EMANUELA BOTTA
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The current standards of assessment are demanding for high level of precision with less time-consuming and personalized opportunities, thus restrict the function of Paper and Pencil Test which has dominated the assessment field for a very long time.
M. A. Samsudin +2 more
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Community-based adaptation (CBA) is becoming an increasingly popular approach to climate change adaptation in the Pacific islands region. Building adaptive capacity should be an important component of projects supporting CBA.
Aalbersberg, William +4 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Adaptive curiosity about metacognitive ability
Metacognition provides control and oversight to the process of acquiring and using knowledge. Across three experiments, we found a specific form of curiosity in humans about the quality of their own metacognition, using a novel approach that dissociates perceptual from metacognitive information searches. Observers displayed a strategic balance in their
Samuel Recht +3 more
openaire +3 more sources

