Results 81 to 90 of about 10,854,095 (294)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Determinant moments for the design management occurrence in fashion industry [PDF]
, 2018 Design management has occupied a privileged place in debates related to the field of design and innovation in fashion industry. The apparel industry, in particular, presents a dynamic character, requiring constant updates on raw materials, changes in ...
Libânio, Cláudia de Souza +5 more
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
An asymptotic scaling analysis of LQ performance of an approximate adaptive control design
, 2002 We consider the adaptive tracking problem for a chain of integrators, where the uncertainty is static and functional. The uncertainty is specified by L2/L∞ or weighted L2/L∞ norm bounds. We analyse a standard Lyapunov-based adaptive design which utilises
Szepesvari, Cs., Rogers, E., French, M.
core +1 more source
The Significance of Adaptive Design in R&D in Japan
Journal of the Formosan Medical Association, 2008 In the past decade, the number of drug and biological product submissions to the United States Food and Drug Administration has been slowly declining, while biomedical research spending has increased.
Masahiro Takeuchi
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Adaptive hypertext design environments: putting principles into practice
, 2000 This paper discusses the design of a tool for authoring adaptive hypertext. First we describe the task of adaptive hypertext design. The network editing task as well as the testing phase are explored showing the importance of a design environment for ...
Baggio, D. +5 more
core +1 more source
Performance Limitation of Subband Adaptive Equalisers [PDF]
, 2006 The aim of this reported work was identifying and quantifying limitation for the subband adaptive equalisers. The derived Wiener solution is compared against simulations for the subband equaliser, and it is verified that aliasing caused in the subband ...
Mohamod, H. +3 more
core +2 more sources
ADAPTABLE DESIGN FOR DESIGN REUSE
Proceedings of the Canadian Engineering Education Association (CEEA), 2011 Due to the complexity, associated cost, and general uncertainty of performing the creative design process, significant value exists in reusing the design information developed in previous design efforts. This paper outlines the current state of the art in design reuse in various fields as well as identifying both the current and future research areas ...
D. Fletcher, P. Gu
openaire +2 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source