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Adaptive evolution of Mediterranean pines [PDF]
Molecular Phylogenetics and Evolution, 2013 Mediterranean pines represent an extremely heterogeneous assembly. Although they have evolved under similar environmental conditions, they diversified long ago, ca. 10 Mya, and present distinct biogeographic and demographic histories. Therefore, it is of special interest to understand whether and to what extent they have developed specific strategies ...
Grivet, Delphine +5 more
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The Stochastic Edge in Adaptive Evolution [PDF]
Genetics, 2008 Abstract In a recent article, Desai and Fisher proposed that the speed of adaptation in an asexual population is determined by the dynamics of the stochastic edge of the population, that is, by the emergence and subsequent establishment of rare mutants that exceed the fitness of all sequences currently present in the population.
Brunet, Eric +2 more
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Fluctuation domains in adaptive evolution [PDF]
Theoretical Population Biology, 2010 We derive an expression for the variation between parallel trajectories in phenotypic evolution, extending the well known result that predicts the mean evolutionary path in adaptive dynamics or quantitative genetics. We show how this expression gives rise to the notion of fluctuation domains - parts of the fitness landscape where the rate of evolution ...
Boettiger, Carl +2 more
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An adjusted ELISpot-based immunoassay for evaluation of SARS-CoV-2-specific T-cell responses
Biosafety and Health, 2022 Like antibody evaluation, using an effective antigen-specific T-cell immunity assessment method in coronavirus disease 2019 (COVID-19) patients, survivors and vaccinees is crucial for understanding the immune persistence, prognosis assessment, and ...
Hao Lin +7 more
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Evolution, Adaptation, and Supercoiling [PDF]
Journal of Bacteriology, 2007 Geometrical and, to some extent, physical and informational properties of covalently closed DNA molecules (or molecules that can be ideally viewed as closed) are determined by their connectivity, i.e., the number of times one strand of DNA is topologically linked to another.
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Frontiers in Physiology, 2022 Global warming is becoming the future climate trend and will have a significant impact on small mammals, and they will also adapt at the physiological levels in response to climate change, among which the adaptation of energetics is the key to their ...
Jiahong Feng +7 more
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The Adaptive Evolution Database (TAED) [PDF]
Genome Biology, 2001 The Master Catalog is a collection of evolutionary families, including multiple sequence alignments, phylogenetic trees and reconstructed ancestral sequences, for all protein-sequence modules encoded by genes in GenBank. It can therefore support large-scale genomic surveys, of which we present here The Adaptive Evolution Database (TAED).
Liberles, David +4 more
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Journal of Functional Biomaterials, 2023 Atopic dermatitis (AD) is the most common heterogeneous skin disease. Currently, effective primary prevention approaches that hamper the occurrence of mild to moderate AD have not been reported.
Shengnan He +6 more
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Biosafety and Health, 2023 Understanding how human leukocyte antigen (HLA) polymorphism affects both the susceptibility and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection will help to identify individuals at higher risk to better manage and ...
Xin Wang +12 more
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