Results 51 to 60 of about 277,643 (313)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

EVOLUTION AND ADAPTATION [PDF]

The American Journal of the Medical Sciences, 1904
n ...
  +8 more sources

Evolution: Informational Constraints on Adaptation [PDF]

Current Biology, 2004
Many species adaptively alter offspring sex ratios, yet little is known about how they obtain relevant environmental information. New work on the parasitoid wasp Nasonia vitripennis reveals that the presence of eggs on hosts provides a reliable cue allowing females to determine the degree of local mate competition and adaptively adjust offspring sex ...
openaire   +4 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Adaptive Evolution on Neutral Networks [PDF]

Bulletin of Mathematical Biology, 2001
We study the evolution of large but finite asexual populations evolving in fitness landscapes in which all mutations are either neutral or strongly deleterious. We demonstrate that despite the absence of higher fitness genotypes, adaptation takes place as regions with more advantageous distributions of neutral genotypes are discovered.
openaire   +4 more sources

Rapidly evolving genes and stress adaptation of two desert poplars, Populus euphratica and P. pruinosa

, 2013
Understanding which genes have evolved rapidly with the recent tree speciation in arid habitats can provide valuable insights into different adaptation mechanisms. We employed a comparative evolutionary analysis of expressed sequence tags (ESTs) from two
Penghui Xie (420345), Zhang, Jian, Jianquan Liu (200999), Zhang Jian, Meagher Thomas R., Meagher, Thomas R., Lascoux, Martin, Xie, Penghui, Liu, Jianquan, Thomas R Meagher, Xie Penghui, Lascoux Martin, Martin Lascoux, Jian Zhang (1682), Martin Lascoux (201001), Jianquan Liu, Liu Jianquan, Jian Zhang, Lascoux, Martin,, Thomas R. Meagher (420346), Meagher, Thomas Robert, Penghui Xie   +21 more
core   +1 more source

Linearity considerations in adaptive antenna array applications [PDF]

, 1995
The use of adaptive antenna in mobile communications base stations is self-explanatory. It offers the potential of increased spectrum efficiency, extended range of coverage and reduced delay spread.
Xue, H, Davies, RL, McGeehan, JP, Beach, MA   +3 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Intermittent fasting driven different adaptive strategies in Eothenomys miletus (Red-backed vole) at different altitudes: based on the patterns of variations in intestinal microbiota

BMC Microbiology
In the face of global warming, the Eothenomys miletus (Red - backed vole), a species dwelling in highland mountainous regions, is likely to encounter difficulties. Given its restricted mobility, it may struggle with the uncertainty of food resources.
Ting Jia, Wei Zhang, Wanlong Zhu, Lixian Fan   +3 more
doaj   +1 more source

Detecting non-Brownian trait evolution in adaptive radiations

, 2006
Many phylogenetic comparative methods that are currently widely used in the scientific literature assume a Brownian motion model for trait evolution, but the suitability of that model is rarely tested, and a number of important factors might affect ...
Harvey, Paul H., Freckleton, Robert P., Paul H Harvey, Robert P Freckleton, Harvey, P.H., Freckleton, R.P.   +5 more
core   +1 more source