Results 101 to 110 of about 16,616 (239)

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

A Rapid Nondestructive Detection Method for Liquor Quality Analysis Using NIR Spectroscopy and Pattern Recognition

Applied Sciences
Liquor has a complex system with high dimensional components. The trace components in liquor are varied and have low content and complex coordination relationships. This study aimed to solve the problem of reliance on smell and taste.
Guiyu Zhang, Xianguo Tuo, Yingjie Peng, Xiaoping Li, Tingting Pang   +4 more
doaj   +1 more source

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

Advanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton, Carrillo Paola Gonzalez, Luay Almassalha, Wing Shun Li, Ruyi Gong, Nicolas Acosta, I Chae Ye, Jane Frederick, Christopher Hogg, Saira John, J. A. Gareth Williams, Rikkert J. Nap, Igal Szleifer, Vadim Backman   +13 more
wiley   +1 more source

Bistable Networks Enable Complex Shape Changes

Advanced Science, EarlyView.
Transition‐controlled metamaterials are networks of bistable mechanical memory that store local binary states and express them as global shape change. By decoupling low‐force programming from high‐force holding, a single lattice is reconfigured into distinct 2D profiles and 3D surfaces without continuous actuation, enabling reusable morphing materials ...
Sawyer Thomas, Jeffrey Lipton
wiley   +1 more source

Nondestructive prediction of leaf area in colored cotton cultivars: a comparative approach using machine learning models with an interactive web interface

Journal of Cotton Research
Background Leaf area is a crucial indicator of plant growth and physiology, with direct measurements being destructive to the plant. This study aimed to develop and compare machine learning models [support vector regression (SVR), adaptive neuro-fuzzy ...
João Everthon da SILVA RIBEIRO, Antonio Gideilson Correia da SILVA, Pablo Henrique de ALMEIDA OLIVEIRA, Ester dos SANTOS COÊLHO, Rislayne Ingrid FAGUNDES, Ramon Silva MELO, Carlos Daniel de SOUZA MORAIS, Diego Mendonça SANTOS, Lindomar Maria da SILVEIRA, Aurélio Paes BARROS JÚNIOR   +9 more
doaj   +1 more source

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

Advanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao, Jinyu Cheng, Feng‐ao Wang, Chenxin Yi, Jiajun Chen, Keyue Wang, Lulu Liu, Junwei Liu, Yixue Li   +8 more
wiley   +1 more source

Estimating tornado occurrence and tornado wind hazard in China

Weather and Climate Extremes
Tornadoes can potentially damage structures and cause fatalities. Although tornado occurrence is often observed in China's mainland, a systematic development of a comprehensive catalogue that forms the basis for tornado hazard assessment and mapping was ...
Y.X. Liu, Y. Zhang, H.P. Hong
doaj   +1 more source

Analog Synaptic Plasticity in 2D Layered Material Iontronic Memtransistors for Brain‐Inspired Computing

Advanced Science, EarlyView.
In this work, we demonstrated a robust 2D MoS2 based iontronic memtransistor of planar architecture operated under the influence of an electrical double layer with versatile performance and applications, including pinched hysteresis nature of transfer curve, analogue channel conductance tuning, low‐voltage operation, logic‐gate operation, classical ...
Puranjay Saha, Saptarshi Bej, Bikas C. Das   +2 more
wiley   +1 more source

Fault Diagnosis of Rolling Bearing Based on Spectrum-Adaptive Convolution and Interactive Attention Mechanism

Machines
With the development of artificial intelligence technology, intelligent fault diagnosis methods based on deep learning have received extensive attention.
Hongxing Zhao, Yongsheng Fan, Junchi Ma, Yinnan Wu, Ning Qin, Hui Wang, Jing Zhu, Aidong Deng   +7 more
doaj   +1 more source

α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths

Advanced Science, EarlyView.
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel, Soumik Ray, Federica Saraceno, Giacomo Nisini, Georgia Nasi, Thomas Oliver Mason, Antonin Kunka, Effrosyni Agrimaki, Dannie Juul Olesen, Francesco Simone Ruggeri, Alexander K. Buell   +10 more
wiley   +1 more source