Pediatric Investigation, EarlyView.This study elucidates the critical pathogenic mechanisms of pediatric Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis (EBV‐HLH), where EBV infection triggers a cytokine storm leading to immune cell hyperactivation and tissue damage. Dynamic plasma biomarkers (EBV‐DNA, ferritin, and interferon‐γ) effectively predict treatment response ...
Feifei Liu +9 more
wiley +1 more source
Exploratory multivariate adaptive regression splines modeling of myopic progression in children receiving atropine. [PDF]
J Chin Med AssocChen JW, Yu CH, Liu TC, Lu CJ, Wu TE.
europepmc +1 more source
Adjustment set selection for estimating optimal treatment rules under confounding. [PDF]
Psychol MethodsGalanter N, Shortreed SM, Moodie EEM.
europepmc +1 more source
Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions
Portal Hypertension &Cirrhosis, EarlyView.This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley +1 more source
Variable selection-combined causal mediation analysis for continuous treatments with application to large-dimensional biomedical data. [PDF]
PLoS Comput BiolZhou Y +6 more
europepmc +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Earth's ecosystems are experiencing wide‐ranging impacts from global climate change, including increased average and extreme temperatures. These temperature shifts can drastically affect plant physiology, threatening the future of even common plant species. Here, we focus on photosynthetic function in a native Southern California shrub species.
Anna K. M. Bowen +8 more
wiley +1 more source
Data-driven modeling of supercritical CO₂ processing with optimized machine learning: prediction of clobetasol propionate solubility. [PDF]
Front Med (Lausanne)Abu-Hamdeh NH, Ajour MN.
europepmc +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Anthropogenic facilitation of wild plants based on aesthetic preferences for particular traits can change the biogeography and ecology of natural communities. We use a mixed‐methods socioecological approach to characterize the ways in which humans interact with a common, widely distributed plant and a generalist viral symbiont that induces an ...
Elizabeth M. Lombardi +3 more
wiley +1 more source
Identification and validation of a robust inflammation-related three-gene signature for the diagnosis of neonatal necrotizing enterocolitis via machine learning integration. [PDF]
Pediatr Surg IntYuan L, Wang X, Wong KKY.
europepmc +1 more source
Precision agriculture for water saving: The case of processing tomato and table grape
PLANTS, PEOPLE, PLANET, EarlyView.Agriculture faces increasing pressure to produce high‐quality food while reducing water use under intensifying climate change and water scarcity. This study compared sensor‐based precision irrigation, drone monitoring, and near‐infrared spectroscopy with conventional farmer management in table grape and processing tomato production systems.
Giuseppe Ferrara +6 more
wiley +1 more source