Results 31 to 40 of about 309,335 (260)

Harmonised observations of climate forcing across Africa: an assessment of existing approaches and their applicability

Environmental Research Letters, 2020
A crucial aspect of coordinated climate action is the ability to measure, attribute, report and verify the drivers of climate change not only globally, but down to national level.
Ana López-Ballesteros, Johannes Beck, Jörg Helmschrot, Matthew Saunders   +3 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Insect resistance responses of ten Aster varieties to damage by Tephritis angustipennis in the three rivers source region of China

Scientific Reports
Aster varieties are widely used for medicinal purposes, landscaping, and ecological restoration, but their growth and reproduction are significantly threatened by the seed predator Tephritis angustipennis (Diptera: Tephritidae).
Li-Jun Zhang, Ying Liu, Yu-Shou Ma, Yan-Long Wang, Xin-You Wang, Yuan Ma, Le-Le Xie   +6 more
doaj   +1 more source

The system of investment and construction project management as a component of the company’s sustainable development

Вестник университета, 2023
Investment and construction companies that have adopted the principles of sustainable development need to transform the project management system accordingly.
O. E. Astafyeva, S. V. Sianin
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Changes of soil bacterial community composition and functional groups in different altitude gradients of Potentilla fruticosa shrub in eastern Qinghai-Tibet Plateau

Frontiers in Plant Science
IntroductionSoil properties and extracellular enzyme activities are the key factors affecting microbial communities at different altitudes. It is very important to understand their distribution patterns along the elevation gradient for predicting the ...
Lele Xie, Lele Xie, Yushou Ma, Yushou Ma, Yanglong Wang, Yanglong Wang, Yuan Ma, Yuan Ma, Ying Liu, Ying Liu   +9 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

One threat, two solutions: Grazing drives divergent adaptive strategies in two dominant Alpine grassland species

Environmental and Experimental Botany
Herbivory is a major selective pressure shaping plant evolution, and the responses of plants to herbivory are typically explained by the growth-defense balance hypothesis (GDBH). However, GDBH often oversimplifies the effects of herbivore types and fails
Wenting Liu, Yuzhen Liu, Yang Yu, Xiaoxia Yang, Chunping Zhang, Quanmin Dong   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Analysis of spatial and temporal distribution of grassland yield under grassland ecological subsidy policy

Scientific Reports
The Three River Headwater Region is an ecologically sensitive and fragile area. The analysis of long-term grassland yield changes, as well as the impact of climate and topography on grassland yield is of great significance to grassland ecological ...
ZhanMing Qiao, Feng Lai, ZengLian Xiong, QuanMin Dong, Yang Yu, ChunPing Zhang, Quan Cao   +6 more
doaj   +1 more source