Results 91 to 100 of about 801,080 (268)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Adaptive Car Following Model

Journal of Mechanical Engineering, 2018
The vehicle dynamics was a very lot developed in the last twenty years. There is a huge gap in the different vehicle models in this field. Researchers need accurate the car following models because of it.
Mika Péter
doaj   +1 more source

Early‐Phase Research in Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Adaptive model training strategy for continuous classification of time series. [PDF]

Appl Intell (Dordr), 2023
Sun C, Li H, Song M, Cai D, Zhang B, Hong S.   +5 more
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Outlook towards deployable continual learning for particle accelerators

Machine Learning: Science and Technology
Particle accelerators are high power complex machines. To ensure uninterrupted operation of these machines, thousands of pieces of equipment need to be synchronized, which requires addressing many challenges including design, optimization and control ...
Kishansingh Rajput, Sen Lin, Auralee Edelen, Willem Blokland, Malachi Schram   +4 more
doaj   +1 more source

An Adaptive Model Filtering Algorithm Based on Grubbs Test in Federated Learning. [PDF]

Entropy (Basel), 2023
Yao W, Pan B, Hou Y, Li X, Xia Y.
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Development of adaptive thermal comfort model for urban park based on field survey and literature review

Frontiers in Built Environment
Global warming has caused an increase in extreme heatwaves. Research on outdoor thermal comfort in urban parks has been carried out in different countries under various climatic conditions. However, there is lack of information on outdoor thermal comfort
Rupendra Subedi, Hom B. Rijal, Supriya Khadka, Naja Aqilah, Prativa Lamsal   +4 more
doaj   +1 more source