Results 161 to 170 of about 485,680 (303)
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
The Concept of Space-Time Spreading (STS) assisted, Adaptive Quadrature Amplitude Modulation (AQAM) aidedMC DS-CDMAis introduced. The AQAMmode-switching thresholds are determined using an on-line real-time Bit-Error-Ratio (BER) based learning procedure ...
Hanzo, L., Wei, H, Yang, L-L.
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
QRD-Assisted Adaptive Modulation-Aided MIMO Systems
—In this paper, we propose QR-decomposition (QRD)-based adaptive modulation (AM)-aided multiple-input–multiple-output (MIMO) systems. The proposed algorithm yields a tight lower bound of the free distance (FD), which determines the error probability of ...
Hanzo, Lajos +3 more
core
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
The Emerging Role of Biomarkers in Adaptive Modulation of Clinical Brain Stimulation. [PDF]
Hoang KB, Turner DA.
europepmc +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Commentary: The Emerging Role of Biomarkers in Adaptive Modulation of Clinical Brain Stimulation. [PDF]
Gunduz A.
europepmc +1 more source
Combine ultrafast wavefront shaping adaptive optomechatronics technologies (build in WP3 and WP4) in one microscopy enabled ...
openaire +1 more source

