Results 91 to 100 of about 3,480,946 (289)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Adaptive Social Protection: A Systematic Literature Review and Research Agenda

Policy & Governance Review
Adaptive social protection represents a novel form of approach that is more holistic in addressing issues related to disasters associated with climate change and social shifts. Adaptive social protection has resurfaced social protection as a new approach
Ita Prihantika, Tia Panca Rahmadhani, Nana Mulyana   +2 more
doaj   +1 more source

Radiation Worker Protection by Exposure Scheduling

Dose-Response, 2011
The discovery of the protective adaptive response of cells to a low dose of radiation suggests applications to radiation worker/first responder protection. Its use in cancer radiotherapy has been discussed in a separate publication.
Richard Blankenbecler
doaj   +1 more source

Immunogenicity mechanism of mRNA vaccines and their limitations in promoting adaptive protection against SARS-CoV-2. [PDF]

PeerJ, 2022
Salleh MZ, Norazmi MN, Deris ZZ.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

µPMU-based smart adaptive protection scheme for microgrids

Journal of Modern Power Systems and Clean Energy, 2019
The concepts of microgrids (MGs) and smart grid represent the recent targeted revolution towards fully smart electrical network integrated with high penetration of renewable energy sources (RESs).
Mohamed Salah Elbana, Nabil Abbasy, Ashraf Meghed, Nahil Shaker   +3 more
doaj   +1 more source

Adaptive protection coordination scheme in microgrids using directional over-current relays with non-standard characteristics. [PDF]

Heliyon, 2021
Saldarriaga-Zuluaga SD, López-Lezama JM, Muñoz-Galeano N.   +2 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Hepatic Autophagy Deficiency Remodels Gut Microbiota for Adaptive Protection via FGF15-FGFR4 Signaling. [PDF]

Cell Mol Gastroenterol Hepatol, 2021
Yan S, Khambu B, Chen X, Dong Z, Guo G, Yin XM.   +5 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source