Results 131 to 140 of about 3,459,920 (290)
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Adaptive current protection for three‐phase short‐circuit faults in active distribution networks
To address the impact of distributed generation (DG) access on the traditional protection configuration methods of distribution networks (DNs) and to facilitate the swift and effective protection of lines by protection devices under fault conditions, an ...
Shi Su +7 more
doaj +1 more source
Remifentanil functions in the adaptive protection of cardiac function following ischemia. [PDF]
Hou J, Wang H, Li X, Zhu Y.
europepmc +1 more source
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Background Globally, the disease ecology of reptiles remains understudied, even for threatened and iconic species such as the Galápagos marine iguana (Amblyrhynchus cristatus).
Flora Uesseler +9 more
doaj +1 more source
Title from cover.; At head of title: State of Connecticut.; "Changing the Balance."; "Pursuant to Connecticut General Statutes Section 22a-228 and 22a-228-1(b) of the Regulations of Connecticut State Agencies (RCSA) ..."--T.p.
Connecticut. Dept. of Environmental Protection.
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ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
Modelling and control of adaptive mechanical structures Proceedings
Adaptive structures (smart structures) are autonomous structural systems with integrated multifunctional smart materials as actuators and sensors, connected by a control system, to facilitate adaptation to changing environmental conditions (e.g.
Gabbert, U. (comp.) +1 more
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Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli +13 more
wiley +1 more source

