Results 71 to 80 of about 239,145 (260)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Research on a dynamic security defense system for cloud-native education platforms using mixture-of-experts model

Dianzi Jishu Yingyong
To address the complex dynamic security threats confronting cloud-native education platforms and the limitations of traditional defense mechanisms—notably weak environmental awareness, lack of intelligent decision-making, inadequate generalization ...
Xu Wenjing, An Ning, Liu Zhuhui, Yu Zhong   +3 more
doaj   +1 more source

Adaptive electrothermal protection means for semiconductor converters.

Tekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2017
Thermal management for power converters during normal operation and transient modes when electrical components are warmed up is an actual problem. This can be particularly important for converters with intermittent duty operation, e.g. power supplies for
R. A. Baraniuk, V. A. Todorenko, O. F. Bondarenko   +2 more
doaj   +1 more source

An Adaptive Protection System for Sensor Networks Based on Analysis of Neighboring Nodes. [PDF]

Sensors (Basel), 2021
Gamec J, Basan E, Basan A, Nekrasov A, Fidge C, Sushkin N.   +5 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

µPMU-based smart adaptive protection scheme for microgrids

Journal of Modern Power Systems and Clean Energy, 2019
The concepts of microgrids (MGs) and smart grid represent the recent targeted revolution towards fully smart electrical network integrated with high penetration of renewable energy sources (RESs).
Mohamed Salah Elbana, Nabil Abbasy, Ashraf Meghed, Nahil Shaker   +3 more
doaj   +1 more source

Immunogenicity mechanism of mRNA vaccines and their limitations in promoting adaptive protection against SARS-CoV-2. [PDF]

PeerJ, 2022
Salleh MZ, Norazmi MN, Deris ZZ.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Adaptive protection coordination scheme in microgrids using directional over-current relays with non-standard characteristics. [PDF]

Heliyon, 2021
Saldarriaga-Zuluaga SD, López-Lezama JM, Muñoz-Galeano N.   +2 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source