Results 41 to 50 of about 239,145 (260)

Adaptive undervoltage protection scheme for safety bus in nuclear power plants

Nuclear Engineering and Technology, 2022
In the event of a short-circuit accident on a 4.16 kV non-safety bus, the voltage is temporarily lowered as backflow occurs on the safety bus. In such cases, the undervoltage relay of the safety bus shall not pick up the undervoltage so as not to ...
Choong-koo Chang
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Adaptive Hybrid Overcurrent Protection Scheme with High Shares of Distributed Energy Resources

Energies
In this research paper, an adaptive and intelligent protection scheme is developed that brings selectivity and sensitivity to the conventional overcurrent relays considering the changes in grid topologies, changes in grid operation modes, and changes in ...
Gourab Banerjee, Christian Hachmann, Jan Lipphardt, Nils Wiese, Martin Braun   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Distributed Coordination Approach for Enhancing Protection System Adaptability in Active Distribution Networks

Energies
The electrical protection of active distribution networks is crucial for ensuring reliable, safe, and flexible operations. However, protecting these networks presents several challenges due to the emergence of bi-directional power flows, network ...
Manuel Acevedo-Iles, David Romero-Quete, Camilo A. Cortes   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Grid Forming Inverter With Increased Short-Circuit Contribution to Address Inverter-Based Microgrid Protection Challenges

IEEE Open Journal of the Industrial Electronics Society
Substantial differences in fault levels between grid-tied and islanded modes is one of the primary challenges of microgrid protection. During grid-tied mode, the bulk grid provides significant short-circuit, while during islanded operation the short ...
Maximiliano Ferrari, Leon M. Tolbert, Emilio C. Piesciorovsky   +2 more
doaj   +1 more source

Zonal Machine Learning-Based Protection for Distribution Systems

IEEE Access, 2022
Adaptive protection is defined as a real-time system that can modify the protective actions according to the changes in the system condition. An adaptive protection system (APS) is conventionally coordinated through a central management system located at
Binod P. Poudel, Ali Bidram, Matthew J. Reno, Adam Summers   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source