Results 41 to 50 of about 256,675 (301)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Adaptive Protection Scheme for Active Distribution Networks Under Two-Phase Short-Circuit Faults Based on Integrated Sequence Components

Energies
The widespread integration of inverter-based distributed generators (IIDGs) severely limits the adaptability of conventional three-step overcurrent protection in distribution networks (DNs).
Shi Su, Yuan Li, Xuehao He, Faping Hu, Yingwei Guo, Jialin Liu, Xiaolong Chen, Botong Li, Jing Zhang   +8 more
doaj   +1 more source

Method of dynamic trust assessment in Zero Trust Architecture based on explainable artificial intelligence

Ìнформаційні технології та компʼютерна інженерія
The transformation of contemporary corporate IT infrastructures has rendered conventional cybersecurity models ineffective, prompting a shift to the Zero Trust Architecture (ZTA); however, its practical implementation is complicated by a rigid reliance ...
A. Palamarchuk
doaj   +1 more source

Multi-Set Space-Time Shift Keying Assisted Adaptive Inter-Layer FEC for Wireless Video Streaming

IEEE Access, 2019
The scalable video coding extension of H.265/high efficiency video coding is capable of supporting diverse video resolutions. Due to the fact that the enhancement layer (EL) is encoded and decoded with the aid of the base layer (BL), the decodability of ...
Yanqing Zhang, Ibrahim A. Hemadeh, Mohammed El-Hajjar, Lajos Hanzo   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Strengthening links between social protection and disaster risk management for adaptive social protection in Nepal [PDF]

, 2018
A key challenge in Nepal is the intersection of predictable chronic or seasonal poverty andvulnerability, with rapid-onset and acute shocks. Nepal in the last few decades has epitomized the'perfect storm' in which a number of different factors—disasters,
Ghimire, Anita, Slater, Rachel, Baur, Dani   +2 more
core  

Adaptive undervoltage protection scheme for safety bus in nuclear power plants

Nuclear Engineering and Technology, 2022
In the event of a short-circuit accident on a 4.16 kV non-safety bus, the voltage is temporarily lowered as backflow occurs on the safety bus. In such cases, the undervoltage relay of the safety bus shall not pick up the undervoltage so as not to ...
Choong-koo Chang
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source