Results 101 to 110 of about 956,969 (294)

Reinforcement learning based adaptive control method for traffic lights in intelligent transportation

Alexandria Engineering Journal
Addressing the requirements and challenges of traffic light control, a reinforcement learning based adaptive optimal control model for traffic lights in intelligent transportation systems is proposed.
Zhongyi Huang
doaj   +1 more source

Multi-Agent-Based Data-Driven Distributed Adaptive Cooperative Control in Urban Traffic Signal Timing

Energies, 2019
Data-driven intelligent transportation systems (D2ITSs) have drawn significant attention lately. This work investigates a novel multi-agent-based data-driven distributed adaptive cooperative control (MA-DD-DACC) method for multi-direction queuing ...
Haibo Zhang, Xiaoming Liu, Honghai Ji, Zhongsheng Hou, Lingling Fan   +4 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

A Link-based Mixed Integer LP Approach for Adaptive Traffic Signal Control [PDF]

, 2012
This paper is concerned with adaptive signal control problems on a road network, using a link-based kinematic wave model (Han et al., 2012). Such a model employs the Lighthill-Whitham-Richards model with a triangular fundamental diagram.
Friesz, Terry L., Han, Ke, Yao, Tao
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Evaluating adaptive signal control using CORSIM [PDF]

1998 Winter Simulation Conference. Proceedings (Cat. No.98CH36274), 2002
C. Stallard, L.E. Owen
openaire   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

A Platoon-Based Adaptive Signal Control Method with Connected Vehicle Technology. [PDF]

Comput Intell Neurosci, 2020
Li N, Chen S, Zhu J, Sun DJ.
europepmc   +1 more source