Results 61 to 70 of about 956,969 (294)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Adaptive Neural Constraint Output Control for a Class of Quantized Input Switched Nonlinear System

IEEE Access, 2019
In this paper, an adaptive neural control issue is addressed for a class of switched unknown strict-feedback nonlinear system under constraint output, in which the input signal is quantized.
Zhiliang Liu, Bing Chen, Chong Lin, Yun Shang   +3 more
doaj   +1 more source

Input and Output Performance of M-MRAC in the Presence of Bounded Disturbances [PDF]

, 2011
This paper presents performance analysis of novel modified model reference adaptive control (M-MRAC) architecture in conjunction with different robust adaptive laws for the uncertain linear systems subject to unknown but bounded disturbances. It is shown
Krishnakumar, Kalmanje Srinvas, Stepanyan, Vahram   +1 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

DeepSIGNAL-ITS—Deep Learning Signal Intelligence for Adaptive Traffic Signal Control in Intelligent Transportation Systems

Applied Sciences
Urban traffic congestion remains a major contributor to vehicle emissions and travel inefficiency, prompting the need for adaptive and intelligent traffic management systems. In response, we introduce DeepSIGNAL-ITS (Deep Learning Signal Intelligence for
Mirabela Melinda Medvei, Alin-Viorel Bordei, Ștefania Loredana Niță, Nicolae Țăpuș   +3 more
doaj   +1 more source

Robust high-performance control for robotic manipulators [PDF]

, 1991
Model-based and performance-based control techniques are combined for an electrical robotic control system. Thus, two distinct and separate design philosophies have been merged into a single control system having a control law formulation including two ...
Seraji, Homayoun
core   +1 more source

Multistage Adaptive Estimation of Sparse Signals

, 2013
This paper considers sequential adaptive estimation of sparse signals under a constraint on the total sensing effort. The advantage of adaptivity in this context is the ability to focus more resources on regions of space where signal components exist ...
Hero III, Alfred O., Wei, Dennis
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source