Results 111 to 120 of about 3,509,514 (324)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Exercise, addiction and motivation: the development of a motivation scale in extreme sports as a sport of challenge with nature

Frontiers in Psychology
In the extant literature, the concepts of motivation and addiction have been employed to elucidate how a considerable number of unpleasant experiences for extreme sports participants can eventually become rewarding.
İzzet Karakulak, Özge Yavaş, Mehmet Veysi Bora, Ender Eyuboğlu, Cem Sinan Aslan, Ahmet Aydemir, Sırrı Cem Dinç, Ömür Fatih Karakullukçu, Faik Öz, Fatma Neşe Şahin   +9 more
doaj   +1 more source

Patient-Reported Outcomes Measurement Information System physical function correlates with Toronto Extremity Salvage Score in an orthopaedic oncology population [PDF]

, 2019
Background: The National Institute of Health\u27s Patient-Reported Outcomes Measurement Information System (PROMIS) uses computerised-adaptive testing to reduce survey burden and improve sensitivity.
Calfee, Ryan P, Cipriano, Cara A, Dalton, Jay F, McDonald, Douglas J, O\u27Keefe, Regis J, Ploetze, Kristen L   +5 more
core   +1 more source

ADAPTIVE SPORTS: FEATURES OF ITS ORIGIN AND PROBLEMS OF DEVELOPMENT

Theory and Methods of Physical Education and Sports, 2018
Adaptive sports: features of its origin and problems of development / I. Kohut, T. Kropivnitskaya, I. Goncharenko, V. Marynych, S. Matvieiev // Теорія і методика фізичного виховання і спорту. - 2018. - № 2. - С. 20-24.
Irina Kohut, T. Kropivnitskaya, I. Goncharenko, Viktorya Marynych, Sergey Matvieiev   +4 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Adaptive Judo and neuropathy: a mini review on motor skills, balance, and quality of life improvement

Frontiers in Psychology
IntroductionPeripheral neuropathies are progressive conditions characterized by muscle weakness, impaired balance, and reduced quality of life. Rehabilitation programs and adaptive sports have shown promise in mitigating these effects.
Erika Nerozzi, Valeria Prada, Valeria Prada, Francesco Pegreffi, Francesco Pegreffi, Marina Grandis, Angelo Schenone, Emanuela Pierantozzi   +7 more
doaj   +1 more source

ADAPTIVE PHYSICAL EDUCATION AND SPORTS

Interexpo GEO-Siberia, 2019
The article provides information about physical education and sports for people with disabilities. Theoretical basis of the study is taken from regulatory legal acts, as well as scientific literature. The methodological basis of the research are the methods of analysis and synthesis, observation and comparison, system and historical methods, methods of
Evgeny Mitrokhin, Alexandr Antonov
openaire   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Unlocking the power of play: exploring the benefits of traditional games for adapted sports in people with cerebral palsy: a scoping review

Physiotherapy Quarterly
Introduction Adapted physical education is a viable way to improve physical activity in individuals with cerebral palsy. While there is adequate documentation on adapting western games, low- and middle-income countries may lack these resources ...
Mansoor Rahman A, Jagadish Kumar
doaj   +1 more source