Genetic diversity and differentiated adaptive strategies for underrepresented populations at the crossroad of Southeast and East Asia. [PDF]
Li X +8 more
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Heat stress in dairy buffalo: biometeorological, molecular, and adaptive strategies for climate change resilience in subtropical regions. [PDF]
Ismail EM +4 more
europepmc +1 more source
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Adaptive strategies of a medical school during Sudan's armed conflict. [PDF]
Taha MH +3 more
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Gut Microbiota Assembly and Host Phenotypic Variation: Core Adaptive Strategies of <i>Triplophysa yarkandensis</i> (Cypriniformes: Nemacheilidae) to Saline-Alkaline Stress. [PDF]
Chen H +10 more
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Cognitive control in music: adaptive strategies for relative pitch across the absolute-pitch proficiency continuum. [PDF]
Shibayama K, Shimada H, Itoh K.
europepmc +1 more source

